正常成人肾脏磁共振扩散加权成像研究  

Diffusion Weighted MR Imaging in Normal Human Kidney

作　　者：秦卫和[1] 付飞先[1] 陈艳姣[1] 黎晶[1] 杨咏梅[1] 陈学文[1] 

机构地区：[1]湖南省益阳市中心医院影像中心,湖南益阳413000

出　　处：《中国医学影像学杂志》2012年第4期244-247,共4页Chinese Journal of Medical Imaging

基　　金：湖南省卫生厅科研计划项目(B2010-117)

摘　　要：目的通过测量正常成人肾脏磁共振扩散加权成像(DWI)时的表观弥散系数(ADC)值,为肾脏病变患者在DWI成像时提供正常对照标准。资料与方法20例健康志愿者均行MRI常规平扫及DWI成像,DWI成像时b值分别采用0s/mm2、200s/mm2、500s/mm2、800s/mm2、1000s/mm2。结果不同b值下双侧肾脏皮髓质ADC值及双侧肾脏平均ADC值差异有统计学意义(F=57.863～240.324,P=0.000),双侧肾脏皮髓质ADC值及平均ADC值均高于肝、脾及胰腺ADC值。双侧肾脏皮质在不同b值下的ADC值均高于髓质,差异有统计学意义(t=8.436～20.281,P=0.000)。左侧肾脏皮、髓质ADC值及平均ADC值在b=500s/mm2、b=800s/mm2及1000s/mm2时均高于右侧,差异有统计学意义(b=800s/mm2时t=2.023,P=0.048;其余P=0.000)。b=200s/mm2时双侧肾脏皮、髓质ADC值及平均ADC值之间差异无统计学意义(t=1.739,P=0.098;t=0.704,P=0.490;t=-0.314,P=0.757)。结论正常成人肾脏ADC值在不同b值下有差异,双侧肾脏平均ADC值亦存在差异。Purpose To measure the apparent diffusion coefficient（ADC） in kidneys of healthy volunteers.Materials and Methods Twenty healthy volunteers underwent transaxial fat-saturated echo-planar DWI MR imaging of the kidneys during normal breathing.Regions of interest were delineated manually in the cortex and medulla of the kidneys.ADC values of all b values（b = 0s/mm 2,200s/mm 2,500s/mm 2,800s/mm 2,1000s/mm 2） were calculated.Results In all volunteers,ADC values were significantly higher in the cortex than in the medulla（F low = 57.863,F high = 240.324,P = 0.000）.When b values were 500s/mm 2,800s/mm 2 and 1000s/mm 2,AD,C values of left kidney were significantly higher than right kidney（t low = 8.436,t high = 20.281,P = 0.000）.When b value was 200s/mm 2,there was no significant difference between left kidney and right kidney（t=1.739,P = 0.098;t = 0.704,P = 0.490;t =-0.314,P = 0.757）.ADC values of kidney were higher than liver,spleen and pancreas.Conclusion ADC values in the kidneys of healthy volunteers are different at different b values,and the mean ADC values are different between left kidney and right kidney.

关 键 词：肾 磁共振成像 弥散 扩散加权成像 表观弥散系数 

分 类 号：R334.1[医药卫生—人体生理学] R445.2[医药卫生—基础医学]