肿痛安胶囊治疗痰血瘀滞型膝骨关节炎疗效观察  

Effect observation on the Zhongtong'an Capsule in the treatment of knee osteoarthritis with the syndrome of phlegm and blood stasis

作　　者：陈黎明[1] 郭盛君[1] 马玉峰[2] 

机构地区：[1]北京中医药大学第三附属医院脊柱关节科,北京100029 [2]北京中医药大学,北京100029

出　　处：《中国医药导报》2012年第12期128-130,共3页China Medical Herald

摘　　要：目的初步观察肿痛安胶囊与独一味胶囊治疗痰血瘀滞型膝骨关节炎疗效。方法将120例辨证为痰血瘀滞型膝骨关节炎患者随机分为试验组、对照组,分别给予肿痛安胶囊、独一味胶囊口服,2粒,3次/d。观察治疗前后症状体征评分、WOMAC积分、综合疗效等变化,最终评估两者的疗效。结果两组在治疗前、用药2周后的症状体征评分、WOMAC评分,两组间差异无统计学意义(P>0.05)。在用结束后,组间症状体征评分、WOMAC积分差异有统计学意义(P=0.047、0.035)。治疗结束后综合疗效方面比较,差异有统计学意义(P=0.041)。结论肿痛安胶囊较独一味胶囊治疗痰血瘀滞型膝骨关节炎具有更好的疗效,值得推广及进一步研究其作用机制。Objective To observation the effect on the Zhongtong＇an Capsule and Duyiwei Capsule in the treatment of knee osteoarthfitis with the syndrome of phlegm and blood stasis. Methods 120 patients with knee osteoarthritis with the syndrome of phlegm and blood stasis were divided into treatment group and control group, treatment group and control group were given Zhongtong＇an Capsule and Duyiwei Capsule respectively, 2 grains, 3 times a day. Symptoms and signs score, / WOMAV score, general efficacy of two groups were observed before and after treatment. Results There were no significant differences in Symptoms and signs score and WOMAV score between the two groups before treatment and after treatment of 2 weeks （P 〉 0.05）. There were significant differences in Symptoms and signs score and WOMAV score after treatment （P = 0.047, 0.035）. there was significant difference in the general efficacy between the two groups after treatment （P = 0.041）. Con- clusion Zhongtong＇an Capsule has a better effect in the treatment of knee osteoarthritis with the syndrome of phlegm and blood stasis, which compared with Duyiwei Capsule, so it is worthy to be popularized and studied its mechanism of action.

关 键 词：肿痛安胶囊 痰血瘀滞 膝骨关节炎 疗效 

分 类 号：R684.3[医药卫生—骨科学]