心脏再同步治疗对慢性心力衰竭患者的近期疗效观察  

Clinical short-term observation of resynchronization therapy for patients with chronic heart failure

作　　者：马凌[1] 张卫泽[1] 张玉秀[1] 陈永清[1] 王菲[1] 李涛[1] 郭亮[1] 敖雪玲[1] 张汉平[1] 

机构地区：[1]兰州军区兰州总医院心血管内科,甘肃兰州730050

出　　处：《西北国防医学杂志》2011年第6期452-454,共3页Medical Journal of National Defending Forces in Northwest China

摘　　要：目的:观察心脏再同步起搏治疗对慢性心力衰竭的临床疗效。方法:31例慢性心力衰竭合并室内传导阻滞患者行心脏再同步起搏治疗,全部患者成功经冠状静脉植入左心室导线,分别于3月和6月随访,观察QRS波宽度,左心室收缩、舒张末内径,左心室射血分数。结果:心脏再同步治疗后患者QRS时限由术前的(160±32)ms减少到术后的(118±21)ms,P<0.05。术后的第3月和第6月,患者LVEDD由术前(74.5±14.1)mm减少到(66.2±9.5)mm、(64.3±11.2)mm,P<0.01;患者LVESD由术前(65.2±10.2)mm减少到(57.3±9.2)mm、(56.2±10.9)mm,P<0.01;LVEF由术前的(0.24±0.09)增加到(0.36±0.11)、(0.38±0.14),P<0.01。结论心脏再同步化治疗是慢性心力衰竭治疗的有效方法。Objective：To observe the short-term effect of resynchronization therapy in patients with chronic heart failure.Methods：Thirty-one patients with chronic heart failure and left branch block received resynchronization therapy,left ventricle leads were implanted into one of the cardiac veins.Results：The heart function of 31 patients was significantly improved after the treatment.The QRS width was reduced from（118±21）ms to（160±32）ms,P﹤0.05.Left ventricular end-diastolic diameter（LVEDD） was decreased from（74.5±14.1）mm to（66.2±9.5）mm,P﹤0.01.Left ventricular end-systolic diameter（LVESD） was decreased from（65.2±10.2）mm to（57.3±9.2）mm,P﹤0.01.Left ventricular ejection fraction（LVEF） was increased from（0.24±0.09）to（0.36±0.11）,P﹤0.01.Conclusion：The biventricular resynchronization therapy is an effective treatment for chronic heart failure.

关 键 词：慢性心力衰竭 心脏再同步治疗 充血性 

分 类 号：R541.6[医药卫生—心血管疾病]