冠心病患者支架置入术前后外周血Lp(a)、hs-CRP及IL-6水平变化的临床意义  

Clinical Significance of Variety of Lp(a),hs-CRP and IL-6 Level before and after Percutaneous Coronary Intervention in Patients with Coronary Heart Disease

作　　者：王秋波[1] 

机构地区：[1]吉林省四平市中心医院心内科,四平136000

出　　处：《中国医药导刊》2011年第11期1857-1858,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨冠心病患者支架置入术前后Lp(a)、Hs-CRP和IL-6水平变化。方法:121例行冠状动脉内支架置入术的冠心病患者,分别在术前、术后24小时检测患者外周血Lp(a)、Hs-CRP和IL-6水平,并选择冠脉造影结果阴性的45例非冠心病者(对照组)进行比较,测定Lp(a)的浓度、Hs-CRP和IL-6水平。结果:术前患者外周血Lp(a)、Hs-CRP和IL-6水平明显高于对照组(P<0.01)。术后患者外周血Lp(a)、Hs-CRP和IL-6水平明显低于术前(P<0.05)。结论:外周血Lp(a)、Hs-CRP和IL-6水平与冠心病密切相关,可为冠心病患者冠状动脉支架置入术后的早期炎定反应的评估指标。Objective：To investigate the variety and clinical significance of Lp（a）,hs-CRP and IL-6 before and after percutaneous coronary intervention（PCI） in patients with coronary heart disease（CHD） Methods：121 CHD patients who have taken PCI and 45 people whose coronarography are normal were enrolled in the study.The serum level of Lp（a）,hs-CRP and IL-6 were tested befor and 24 hours after PCI.Results：Lp（a）,hs-CRP and IL-6 level of patients before PCI were significantly higher than that of normal people（P0.01 ）,and were significantly higher than that before PCI（P0.05）.Conclusion：Lp（a）,hs-CRP and IL-6 levels are sensitive indicators that reflecting the early inflammation after PCI.

关 键 词：冠心病 支架置入 脂蛋白A 超敏C反应蛋白 白介素-6 

分 类 号：R541.4[医药卫生—心血管疾病]