中国儿童幽门螺杆菌感染与缺铁性贫血关系的Meta分析  

Relationship between helicobacter pylori infection and iron-deficiency anemia among the children in China:a Meta analysis

作　　者：张耀东[1,2] 胡群[1] 刘双又[1] 刘爱国[1] 王冠玲[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院儿科,湖北武汉430030 [2]郑州市儿童医院内分泌科

出　　处：《中国妇幼保健》2012年第12期1907-1909,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨中国儿童幽门螺杆菌感染与缺铁性贫血(IDA)的关联程度,为预防IDA提供科学依据。方法:计算机检索中国期刊全文数据库、万方数据库,检索时间从1994～2009年,纳入儿童幽门螺杆菌感染感染与IDA关系的病例对照研究,用meta分析方法对数据进行处理,估计其综合OR值和95%CI。结果:共有4个研究纳入Meta分析。两组采用固定效应模型的Meta分析,合并OR=4.36,95%CI为3.26～5.83。结论:幽门螺杆菌感染与IDA呈高度相关,故对我国儿童应加强卫生健康教育,减少幽门螺杆菌感染机会,预防IDA的发病。Objective：To explore the degree of association between helicobacter pylori infection and iron-deficiency anemia（IDA） among the children in China,provide a scientific basis for prevention of IDA. Methods：CNKI and Wanfang database were retrieved by a compute,the retrieval time was from 1994 to 2008,then the literatures were analyzed by case-control study based on the relationship between helicobacter pylori infection and iron-deficiency anemia among the children,Meta analysis was used to deal with the data,the comprehensive OR value and 95% CI were evaluated. Results：A total of four studies were included into Meta analysis,fixed effect models were used in two groups,the comprehensive OR value and 95% CI were 4.36 and 3.26-5.83,respectively. Conclusion：Helicobacter pylori infection was correlated with IDA,thus,to prevent the occurrence of IDA,enhancing health education and reducing the chance of helicobacter pylori infection are necessary.

关 键 词：幽门螺杆菌 缺铁性贫血 META分析 

分 类 号：R725.5[医药卫生—儿科]