Implant-induced microdamage in osteoporotic bone  

作　　者：YU Zhi-feng TANG Ting-ting QIU Shi-jing 

机构地区：[1]Shanghai Key Laboratory of Orthopaedics Implant, Department of Orthopaedic Surgery, Shanghai Ninth People＇s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 20001, China

出　　处：《Chinese Journal of Traumatology》2012年第2期113-117,共5页中华创伤杂志（英文版）

基　　金：This research was supported by grants from National Natural Science Foundation for the Youth （No. 11002090）, Shanghai Natural Science Foundation （No. 10ZR1417900） and the Program for Key Disciplines of the Shanghai Mu- nicipal Education Commission （No. J50206）.

摘　　要：With the increase of elderly population, more and more implant operations need to be performed in osteoporotic bone, while different forms of microdamage will be produced in peri-implant bone intraoperatively, including high- and low-density diffuse damages, as well as linear cracks. The length and location of the microcracks are the main factors in affecting the biomechanical performance of bone. Suppression of bone remodeling by bisphosphonates may lead to microdamage accumulation, which is often accompanied with the decrease of bonestrength and the increase of bone fragility. Microdamage can be repaired by bone remodeling or mineralization to maintain the strength and structural integrity. Both remodeling and mineralization can affect the bone quality and long-term implant stability, In this paper, we make a brief summary of some important issues and research progresses in this field.

关 键 词：Osteoporosis  postmenopausal Boneremodeling Aged 

分 类 号：TQ342.742[化学工程—化纤工业] O346.5[理学—固体力学]