瑞舒伐他汀联合阿司匹林与单药治疗颈动脉粥样硬化的疗效观察  

The rosuvastatin in combination with aspirin and single-agent treatment of carotid atherosclerosis's efficient observation

作　　者：张颖[1] 黄卫民[1] 杨崇哲[1] 

机构地区：[1]广州市第一人民医院,广东广州510180

出　　处：《心血管病防治知识（学术版）》2012年第2期4-5,共2页Prevention and Treatment of Cardiovascular Disease

摘　　要：目的探究瑞舒伐他汀与阿司匹林联用与单药治疗颈动脉粥样硬化的临床效果。方法选取我院2009年5月至2011年5月间收治的颈动脉粥样硬化患者93例患者作为实验对象,将其随机分为三组,对比分析三组患者应用药物后血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、高敏C反应蛋白指标。结果三组患者血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、高敏C反应蛋白指标均比治疗前具有显著改善,丙组患者指标改善情况更为显著,与其他两组对比具有显著性差异,具有统计学意义(P<0.05)。结论瑞舒伐他汀与阿司匹林联用治疗颈动脉粥样硬化效果较单药应用效果更为显著,疗效确切,值得临床推广应用。Objective Research of rosuvastatin in combination with aspirin for the treatment of carotid atherosclerosis and clinical effect. Methods Selected in our hospital from 2009 May to 2011 May between the treated patients with carotid atherosclerosis in 93 patients as subjects, divided them into three groups, patients of three groups were analyzed using drugs after three serum total cholesterol, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol, high sensitivity C reactive protein index. Results In three groups of patients with serum total cholesterol, triglyceride, three low density lipoprotein cholesterol, high density lipoprotein cholesterol, high sensitivity C reactive protein indicators than before treatment has improved significantly, group C patients indicators to improve the situation is more remarkable, with the other two groups have significant difference, with statistical significance （P〈0.05）. Conclusions Rosuvastatin in combination with aspirin for the treatment of carotid atherosclerosis effect than single drug application effect is more significant, definite curative effect, it is worthy of clinical application.

关 键 词：瑞舒伐他汀 阿司匹林 颈动脉粥样硬化 应用疗效 

分 类 号：R543.4[医药卫生—心血管疾病]