急性心肌梗死延迟冠状动脉介入治疗的临床研究  

Delayed Percutaneous Coronary Intervention for Acute Myocardial Infarction

作　　者：吴咏昕[1] 袁颖[2] 张宏[1] 

机构地区：[1]云南省第一人民医院心内科,昆明650032 [2]云南省第一人民医院急诊内科,昆明650032

出　　处：《实用临床医学（江西）》2012年第2期15-17,共3页Practical Clinical Medicine

摘　　要：目的探讨急性心肌梗死(AMI)延迟冠状动脉介入治疗(PCI)的临床效果。方法将106例AMI患者按随机数字表法分为2组,药物治疗组50例,采用常规药物(肠溶阿司匹林、氯比格雷、他汀类调脂、低分子肝素,据情况予硝酸酯类、血管紧张素转换酶抑制剂、β受体阻滞剂等)治疗;PCI组56例,经药物治疗7～15d后PCI。1年后对2组患者病死率和再发心梗、心绞痛的发生率以及左室射血分数(LVEF)水平的变化进行比较。结果 PCI组再发心梗、心绞痛的发生率明显低于药物治疗组,LVEF明显高于药物治疗组(P<0.05或P<0.01)。结论 AMI延迟PCI能改善患者的预后。Objective To investigate the clinical effects of medicine therapy and delayed percutaneous coronary intervention（PCI） on acute myocardial infarction（AMI）.Methods A total of 106 patients with AMI were randomly divided into two groups.Medicine therapy group（n=50）was treated with conventional drugs（aspirin,clopidogrel,statins,low molecular weight heparin,nitrates,angiotensin converting enzyme inhibitors,β-receptor blockers,etc.）.PCI group（n=56）was given delayed PCI after drug treatment for 7~15 days.The mortality,recurrence of myocardial infarction,incidence of angina and left ventricular ejection fraction（LVEF） were compared between the two groups 1 year after treatment.Results Compared with medicine therapy group,delayed PCI significantly increased LVEF and obviously decreased the mortality,recurrence of myocardial infarction and incidence of angina（P0.05 or P0.01）.Conclusion Delayed PCI can improve the prognosis of AMI.

关 键 词：急性心肌梗死 延迟冠状动脉介入 药物治疗 

分 类 号：R542.22[医药卫生—心血管疾病]