我国农村HIV/AIDS高流行地区肠道寄生虫感染现况调查  

Survey on co-infection with HIV and intestinal parasites in high prevalence areas of HIV/AIDS,China

作　　者：田利光[1] 程国金[2] 陈家旭[1] 蔡玉春[1] 郭俭[1] 童小妹[1] 刘琴[1] 周晓农[1] 

机构地区：[1]1中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,卫生部寄生虫病原与媒介生物学重点实验室,上海200025 [2]安徽省阜阳市疾病预防控制中心

出　　处：《中国血吸虫病防治杂志》2012年第2期168-172,共5页Chinese Journal of Schistosomiasis Control

基　　金：国家重大科技专项(2008ZX10004-011)

摘　　要：目的了解我国农村HIV/AIDS高流行地区HIV和肠道寄生虫合并感染状况。方法采用横断面调查方法,在安徽省阜阳市2个自然村开展流行病学调查,检测居民HIV和寄生虫感染情况。结果共调查769人,其中720人参与了9种常见肠道寄生虫的检测,蛔虫、钩虫、鞭虫、华支睾吸虫、人芽囊原虫、蓝氏贾第鞭毛虫、阿米巴原虫、隐孢子虫、粪类圆线虫感染率分别为0.56%、4.03%、0.28%、0.42%、21.39%、3.89%、1.67%、4.44%、0。肠道蠕虫总感染率为4.72%,原虫总感染率为24.31%;贫血患病率为34.68%;HIV感染率为8.10%;HIV合并肠道蠕虫感染率为2.17%,合并肠道原虫感染率为28.26%,其中合并人芽囊原虫感染率为19.57%;HIV阳性和HIV阴性人群合并隐孢子虫感染率分别为13.04%和4.70%,两者差异有统计学意义(P<0.05)。结论当地肠道蠕虫感染率低,肠道原虫感染率高,HIV阳性人群对隐孢子虫易感性增高。Objective To understand the co-infection status of HIV and intestinal parasites in a HIV/AIDS highly endemic area in China.Methods A cross-sectional survey was carried out in two villages in Fuyang City,Anhui Province,and the infection status of HIV and intestinal parasites were investigated by blood and fecal examinations.Results A total 769 individuals were enrolled in the investigation,and 720 of whom were participated in stool examinations for intestinal parasite infections.The infection rates of parasites were as follows： 0.56% for Ascaris lumbricoides,4.03% for Hookworm,0.28% for Trichuris trichiura,0.42% for Clonorchis sinensis,21.39% for Blastocystis hominis,3.89% for Giardia lamblia,1.67% for Entamoeba spp.,4.44% for Cryptosporidium spp..The overall infection rate of intestinal worms and protozoan were 4.72% and 24.31%,respectively.The prevalence rate of anemia was 34.68%.The prevalence rate of HIV was 8.10%.The co-infection rate of HIV and intestinal helminthes was 2.17%,and that of HIV and intestinal protozoan was 28.26%,of which the co-infection rate of Blastocystis hominis and HIV were 19.57%.There was a significant difference between the infection rates of Cryptosporidium spp.in the HIV-positive group（13.04%） and HIV-negative group（4.70%）（P 0.05）.Conclusions The infection rate of intestinal protozoan is higher than that of intestinal helminthes in local residents.The HIV-positive population is more susceptible to the infection of Cryptosporidium spp..

关 键 词：HIV/AIDS 肠道寄生虫 合并感染 阜阳市 

分 类 号：R512.91[医药卫生—内科学] R38[医药卫生—临床医学]