上中下痛风要方联合西药治疗痛风性肾病对照临床观察  

Controlled Clinical Observation of Treating Gout Nephropathy by SHANGZHONGXIATONGFENGYAOFANG puls Western Medicine

作　　者：李莲花[1] 于卓[1] 

机构地区：[1]黑龙江省中医研究院,黑龙江哈尔滨150036

出　　处：《实用中医内科杂志》2012年第4期45-46,共2页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察上中下痛风要方治疗痛风性肾病的临床疗效。[方法]将60例患者随机分为两组,对照组30例在常规治疗基础上予以促尿酸排泄药痛风利仙,或联合应用尿酸合成抑制剂别嘌醇;治疗组30例在对照组的治疗基础上同时应用上中下痛风要方治疗。两组均以4周为1个疗程,治疗2个疗程后进行疗效判定。[结果]两组在治疗8周后,血尿酸值均较治疗前有明显下降,中药治疗组较对照组有明显下降,中药治疗组24h尿蛋白定量、血尿素氮、血肌酐值较对照组及治疗前有明显下降。治疗组总有效率83.30%,对照组总有效率63.30%,总有效率治疗组优于对照组。[结论]上中下痛风要方治疗痛风性肾病疗效确切。[Objective] To study the clinical efficacy of SHANGZHONGXIATONGFENGYAOFANG in the treatment of gouty nephropathy.[Methods] 60 patients were divided into two groups,30 patients in the control group were given conventional therapy with TONGFENGLIXIAN,a drug to enhance uric acid excretion,with combination of uric acid synthesis inhibitor allopurinol.Thirty patients in the treatment group were treated with SHANGZHONGXIATONGFENGYAOFANG together with conventional therapy.The two groups were both treated for two courses,with four weeks as one course.Clinical efficacy was determined after two courses of treatment.[Results]Two groups in 8 weeks after treatment,serum uric acid values than before treatment has decreased significantly,Chinese medicine treatment group than the control group decreased significantly,the Chinese medicine group 24h quantity of urinary protein,blood urea nitrogen,serum creatinine values than the control group and the treatment is obviously decreased.The clinical efficacy for the treatment group is 83.30%,and 63.30% for the control group.Efficacy for the treatment group is higher than the control group.[Conclusion] The efficacy of SHANGZHONGXIATONGFENGYAOFANG in treatment of gouty nephropathy is confirmed.

关 键 词：痛风性肾病 上中下痛风要方 碳酸氢钠片 痛风利仙 别嘌醇 中西医结合治疗 对照临床观察 

分 类 号：R256.5[医药卫生—中医内科学]