玉林市疑似麻疹病例血清流行病学特征分析  

Serological testing for measles suspected cases in Yulin,Guangxi,2006-2010

作　　者：李劲锋[1] 梁炯明[1] 陆沛超[1] 黄佐妮[1] 宁珺茹[1] 李勇[1] 

机构地区：[1]玉林市疾病预防控制中心,广西玉林537000

出　　处：《中国预防医学杂志》2012年第4期275-277,共3页Chinese Preventive Medicine

摘　　要：目的分析2006-2010年玉林市麻疹疑似病例检测资料,为今后防控麻疹提供科学依据。方法应用IgM-捕获ELISA法检测2006-2010年送检疑似麻疹病例,并对收集的资料进行综合分析研究。结果 2006-2010年玉林市共检测719份散发病例血清样本,麻疹IgM阳性229份,占31.85%,2006-2008年阳性率分别为75.00%、8.46%、37.81%,2009、2010年无实验室确诊病例;风疹IgM阳性134份,占18.64%,占麻疹阴性样本的27.35%(134/490),各年间麻疹、风疹IgM阳性率差异有统计学意义(P<0.005)。出疹后4～14d采集血液麻疹IgM阳性率最高39.49%。各县(市、区)均有麻疹、风疹实验室确诊病例,高峰期在5月;散居儿童麻疹病例占69.43(159/229),以8月龄～2岁最多,占44.10%(101/229),<8月龄占14.85%(34/229),风疹7～13岁最多,占48.51%(65/134);麻疹病例男性154例、女性75例,男女性别比2.05∶1,风疹病例男性76例、女性58例,男女性别比1.31∶1;麻疹确诊病例中散居儿童占69.43%(159/229),风疹以学生最多占86.57%(116/134)。结论 2006-2010年玉林市麻疹、风疹实验室诊断病例较少,但仍应适时开展麻疹强化免疫,给力于麻疹免疫效果监测,巩固防控成效。Objective To analyze the data of measles suspected case testing in Yulin and provide a scientific basis for measles control and prevention.Methods Serum specimens were collected from clinically measles suspect patients and submitted for measles and rubella IgM antibody testing.The 2006-2010 data of measles suspect patient testing were summarized with the method of descriptive epidemiology.Results The positive rate of measles IgM antibody was 31.85%（229/719） on average for measles suspect cases during 2006-2010.The annual positive rates of measles IgM antibody were 75%,8.46% and 37.81% respectively for the year 2006-2008.There was no laboratory confirmed case in 2009 and 2010.The positive rate of rubella IgM antibody was 27.35%（134/490） for measles negative specimens.The measles IgM antibody was the highest（39.49%） for specimens collected around 14 days after the rash of measles.Most measles cases occurred in spring and summer,and reached to peak in May.Infants and young children aged 8 months to 2 years accounted for 44.10%（101/229） of measles cases.The sex ration of measles cases was 2.05∶1（male：female）.Measles cases were confirmed in all cities and districts of Yulin area.A proportion of 69.43%（159/229） of cases were from scattered children.Rubella cases were mainly confirmed in students（86.56%,116/134）.Children aged 7-13 years accounted for 48.51%（65/134） of cases.The sex ratio of rubella cases was 1.31∶1（male：female）.Conclusion Measles confirmed cases have been decreasing in Yulin since 2006.It is important to maintain the high coverage rate of measles vaccination for the eradication of the disease.

关 键 词：疑似麻疹 血清学检测 流行病分析 

分 类 号：R511.1[医药卫生—内科学]