杭州市戊型肝炎流行特征及危险因素研究  

Study on epidemic characteristics and the risk factors of HEV in Hangzhou city

作　　者：孙昼[1] 谢立[1] 祝绯飞[2] 徐哲[3] 童卫胜[4] 

机构地区：[1]杭州市疾病预防控制中心,浙江杭州310021 [2]杭州市拱墅区疾病预防控制中心 [3]建德市疾病预防控制中心 [4]临安市疾病预防控制中心

出　　处：《中国预防医学杂志》2012年第4期278-280,共3页Chinese Preventive Medicine

基　　金：浙江省医药卫生科技资助项目(2011KYB078)

摘　　要：目的了解杭州市戊肝疫情特征及发病的危险因素。方法对杭州市2006-2010年戊肝病例进行描述性流行病学分析。采用病例对照调查方法,选取实验室确诊戊肝病例作为病例组,同期在同所医院就诊,血清戊肝抗体阴性的非感染性疾病患者作为对照组。制定统一的调查表进行调查,资料采用SPSS 13.0单因素和多因素非条件logistic回归分析。结果 2006-2010年,杭州市共报告戊肝病例2 063例,年平均发病率为5.51/10万,年发病率逐年上升,疫情以散发病例为主。多因素logistic回归分析结果显示,在外就餐(OR=1.554;95%CI:1.234～1.958)及与他人共用水杯(OR=1.889;95%CI:1.120～3.184)是危险因素,饭前有洗手习惯(OR=0.370;95%CI:0.184～0.745)是保护因素。结论杭州市戊肝发病呈逐年上升趋势,接触及食源性传播是主要的传播方式,开展餐饮从业人员戊肝检测很有必要。Objective To understand epidemic characteristics and the risk factors of HEV in Hangzhou city.Methods Data from HEV case annual report from 2006 to 2010 was analyzed by descriptive epidemiology.Cases confirmed by laboratory tests were chosen as a case group and the patients who were in the same hospital at the same period with HEV IgM antibody negative were chosen as a control group.Case-control study and unified questionnaire formulate was used to survey.Data was analyzed by unconditional univariate and multivariate logistic regression using SPSS 13.0.Results A total of 2063 cases of HEV were reported from 2006 to 2010 and annual average morbidity was 5.51/lakh.The annual morbidity increased year by year and sporadic cases composed the whole cases.Multivariate non-conditional logistic regressive analysis showed factors as outside eating（OR=1.554;95%CI：1.234~1.958）and sharing watered glass（OR=1.889;95%CI：1.120~3.184）were the prominent risk factors of infection.Factors,such as wash hands before lunch and after,（OR=0.370;95%CI：0.184~0.745）were the protective factors.Conclusions The morbidity of HEV is a rising trend year by year.Person-to-person contact and food were the main transmission route.It is necessary to carry out HEV antibody test among food service personnel.

关 键 词：戊肝 危险因素 病例对照 

分 类 号：R512.6[医药卫生—内科学]