咳喘胶囊的质量标准研究  

Study on Quality Standard for Kechuan Capsule

作　　者：王晓宏 吴云生 屈月玲 

机构地区：[1]陕西康惠制药股份有限公司,陕西咸阳712000 [2]陕西步长制药有限公司,陕西咸阳712000

出　　处：《现代中药研究与实践》2012年第2期63-66,共4页Research and Practice on Chinese Medicines

摘　　要：目的建立咳喘胶囊的质量标准。方法采用TLC法对咳喘胶囊处方中黄芪、麻黄、桔梗进行定性鉴别,应用HPLC对处方中淫羊藿的成分淫羊藿苷进行了含量测定。结果本品定性鉴别薄层色谱特征明显,专属性强;本品中淫羊藿苷含量测定线性范围为10-60 mg· L^-1,平均回收率为98.16%,RSD为0.69%。结论鉴别和含量测定方法简便可靠,重复性好,作为药品标准可有效控制咳喘胶囊的质量。Objetive To establish the quality stangdard for kechuan capsule.Methods TLC was used to identify Eohedrae Herba,Astragal Radix,Platycodons Radix.HPLC was used to determine the content of Icariline.Results The study on the quality control showed that the characteristic of identification by TLC was distinct and specific.The quantification method had the linear range of 10～60mg·L^-1.The average recovery was 98.16% and RSD was0.69%.Conclusion The method for idetification and quantification was simple,realizable and reproducible.It can be used effectively for the quality control of kechuan capsule.

关 键 词：咳喘胶囊 TLC HPLC 淫羊藿苷 质量标准 

分 类 号：R927.1[医药卫生—药学]