从达尔文医学看细菌性阴道病  

Understanding Bacterial Vaginosis in Terms of Darwinian Medicine

作　　者：胡佐鸿[1] 

机构地区：[1]成都市第一人民医院病理科,四川成都610041

出　　处：《医学与哲学（B）》2012年第4期61-63,共3页Medicine & Philosophy(B)

摘　　要：应用达尔文医学理论从病原体及宿主相互作用对细菌性阴道病(BV)进行分析。从病原体的角度看,白带增多是BV病原体成功繁殖传播基因的表现,白带异味有利于BV病原体基因传播,妇产科诸多并发症是BV病原体对宿主的调控;从宿主的角度看,BV白带增多作为症状是宿主的防御,BV白带异味是宿主的欺骗性繁殖策略,BV妇产科诸多并发症减轻了宿主的繁殖投资。得出结论,在祖先环境中对病原体及宿主双方而言BV都是有利的,因而BV相关基因在疾病进化中被选择保留。By the theory of Darwinian medicine the interaction of pathogens and host was analyzed in bacterial vaginosis （BV）. From the perspective of pathogen in BV, a profuse vaginal discharge is a success of gene propagation of pathogens, a malodorous vaginal discharge promotes spread of the pathogens genes, and many complications in obstetrics and gynecol ogy are manipulation of host by BV pathogens. From the perspective of host in BV, symptom of a profuse vaginal dis- charge is the defense of the host, a fishy--smelling vaginal discharge is the deceptive reproductive strategy of the host, and many complications in obstetrics and gynecology reduced the reproductive investment of the host. It is concluded that in the ancestral environment BV benefited both pathogen and host, and then the genes associated with BV were selected in the evolution of disease.

关 键 词：细菌性阴道病 达尔文医学 自私基因 宿主调控 繁殖策略 

分 类 号：R711.31[医药卫生—妇产科学]