变应性鼻炎流行病学调查方法商榷  

On the methods of epidemiological survey on allergic rhinitis

作　　者：王泽海[1] 林文森[2] 王丽[1] 

机构地区：[1]河北省青县人民医院耳鼻咽喉头颈外科,062650 [2]天津市南开医院耳鼻咽喉头颈外科天津市中西医结合耳鼻咽喉科研究所

出　　处：《中国中西医结合耳鼻咽喉科杂志》2012年第2期150-153,共4页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的分别对不同的变应性鼻炎流行病学调查方法及其结果进行比较,准确评价变应性鼻炎患的病率与相关患病因素。方法 2007年4月～2010年5月,通过随机整群和分层抽样,对河北省沧州市农民、渤海湾黄骅市沿海渔民、承德市雾灵山区居民、天津市区市民5230人进行变应性鼻炎患病率及相关患病因素直接面访调查,并随机检测1524例受调查者血清sIgE。结果临床确诊调查地区变应性鼻炎患病率为9.1%,而直接面访调查获得的有关症状发生率为16.7%,差异有统计学意义(P=52.21,P<0.01)。接受血清学检验的调查病例中,11.5%(176/1524)有鼻变应性症状,但其血清sIgE检测结果阴性。结论直接面访结合血清sIgE检测方法所得调查结果更接近实际水平。Objective To investigate the practically feasible methodology for epidemiological survey on the accurate prevalence and related predisposing factors of allergic rhinitis （AR） in a comparative way among several surveying Methods used in our investigation. Methods The survey was carried out in a population with 5230 of cases, out of the villagers in Qingxian County, Hebei Province, fishermen in coastal lines of Huanghua City, Bohai Bay, mountainous people in Wulingshan area, Chengde City, and urban residents in Tianjin, from Apr. 2007 to May 2010, by face to face survey to investigate the prevalence and related predisposing factors of AR. Then, 1524 of cases was randomly selected from them to detect their specific IgE （sIgE） level in serum. Results In this group of cases surveyed, 9.1% were diagnosed clinically with AR, while 16.7% in this group of cases were determined with clinical manifestation of AR as shown by face to face survey, with very significant statistical difference （X^2=52.21, P〈0.01） between them. Among those cases received serum detection of sIgE, 11.5% （176/1524） were seen with AR symptoms but with a negative result of sIgE test. Conclusions The survey method of face to face interview will provide a relatively accurate epidemiological conclusion on the prevalence of AR at a higher level as closer as to its actual incidence, when combined with laboratory test on sIgE content in serum.

关 键 词：变应性鼻炎 流行病学调查 患病率 调查方法比较 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]