丙烯酸、丙烯醇、乙烯基咪唑三元共聚物的合成  

Synthesis of a terpolymer from acrylic acid,allyl alcohol and vinyl imidazole

作　　者：余磊[1,2] 韩雅莉[1] 张卫丽[1] 

机构地区：[1]广东工业大学轻工与化工学院,广州510006 [2]广东食品药品职业学院制药系,广州510520

出　　处：《化工新型材料》2012年第4期153-155,共3页New Chemical Materials

基　　金：国家自然科学基金项目(30772739);广东工业大学轻工化工学院211工程培育项目(20091015)

摘　　要：通过沉淀聚合的方法,采用偶氮二异丁基腈为引发剂,将乙烯基咪唑、丙烯酸、丙烯醇三元共聚,制备了一种具有类似于纤溶酶生物活性的新型高分子。探讨了合成条件对聚合过程、黏度及分子量的影响,并对利用红外光谱(IR)和核磁共振(NMR)对该共聚物进行了结构表征。纤维蛋白平板实验证实该共聚物能溶解血栓。A new kind of fibrinolytic polymer was synthesized by precipitation polymerization with raw materials of acrylic acid,allyl alcohol and vinyl imidazole,and with azobisisobutylnitrile as initiator.The effects of synthesis conditions on the polymerization process,viscosity and molecular weight of obtained copolymers were diseussed.The copolymer was characterized by infrared spectrum（IR） and nuclear magnetic resonance spectrum（NMR）,and its fibrinolytic activity was determined by fibrin plate.

关 键 词：丙烯酸 丙烯醇 乙烯基咪唑 三元共聚物 

分 类 号：O631.3[理学—高分子化学]