肾良恶性占位超声造影定量参数分析的初步研究  

Quantitative analysis of contrast-enhanced ultrasound in renal lesions： a preliminary study

作　　者：燕翠菊[1] 黄备建[1] 王文平[1] 范培丽[1] 李超伦[1] 

机构地区：[1]复旦大学附属中山医院超声诊断科上海市影像医学研究所,上海200032

出　　处：《中华超声影像学杂志》2012年第4期312-315,共4页Chinese Journal of Ultrasonography

基　　金：基金项目：上海市重点学科建设项目（B112）;卫生部公益性行业科研专项经费项目（200802-10）

摘　　要：目的探讨肾良恶性占位超声造影定量参数特点及临床应用价值。方法对60例经病理证实的肾占位行超声造影检查，用Sonoliver定量分析软件行脱机分析，获得最大峰值强度（maximumintensity，IMAx）、上升时间（risetime，RT）、达峰值时间（timetopeak，TTP）、平均渡越时间（meantransittime，mTT）及曲线下面积（areaunderthecurve，AUC）等参数，并进行统计学分析。结果肾良恶性占位超声造影定量参数RT、mTT、AUC差异有统计学意义（P〈0．05），IMAX差异有显著统计学意义（P〈0．01），恶性肿瘤的RT及mTT均小于良性病灶，IMAX与AUC均大于良性病灶。结论超声造影定量参数分析对肾占位性病变的诊断提供了更多的信息。Objective To investigate the value of quantitative analysis in the diagnosis of renal lesions with contrast-enhanced ultrasound. Methods Sixty cases with renal lesions confirmed by surgery and pathology underwent contrast-enhanced ultrasound preoperatively and quantitative analysis retrospectively. The Sonoliver software was applied in the analysis of CEUS imaging and in the reconstruction of quantitative parameter.s. Five parameters were calculated, including the maximum intensity （IMAX）, rise time （RT）,time to peak （TTP）, mean transit time （mTT） and area under the curve （AUC）. Results There were statistically differences in parameters RT, mTT and AUC （P 〈 0.05） and significant differences in parameter IMAX （ P 〈0.01）. In malignant tumors, the RT and mTT were less than that of the benign while IMAX and AUC were more than that of the benign. Conclusions Contrast-enhanced ultrasound using a quantitative parametric analysis offers more information and is a promising tool in the diagnosis and differentiation of renal masses.

关 键 词：肾占位性病变 超声造影检查 定量参数 良恶性 统计学分析 临床应用价值 曲线下面积 病理证实 

分 类 号：R445.1[医药卫生—影像医学与核医学]