内毒素、C-反应蛋白、血培养对儿童脓毒症早期诊断的意义  

Significance of Endotoxin,C-Reactive Protein and Hemoculture for Early Diagnosis of Sepsis in Pediatrics

作　　者：孙东明[1] 董巧丽[1] 杨小巍[1] 许月红[1] 

机构地区：[1]河北大学附属医院,河北保定071000

出　　处：《实用预防医学》2012年第4期594-595,共2页Practical Preventive Medicine

摘　　要：目的探讨儿童脓毒症检测内毒素、C-反应蛋白(CRP)及血培养的诊断价值及临床意义。方法检测50例脓毒症患儿及对照组30例无感染征象儿童血内毒素、CRP浓度及血培养。结果 50例脓毒症患儿血内毒素及CRP浓度增高,较对照组差异有统计学意义,其中革兰阴性菌(G-菌)感染患儿血内毒素增高更明显。结论内毒素联合CRP检测可作为鉴别G-菌与革兰阳性菌(G+菌)感染的快速诊断方法之一。Objective To explore the diagnosis value and clinical significance of endotoxin,C-reactive protein（CRP） and hemoculture for sepsis in pediatrics.Methods Plasma endotoxin,CRP and hemoculture were determined in 50 children with sepsis and 30 children without infection signs as controls.Results Plasma endotoxin and CRP of children with sepsis were significantly higher than those of the controls（P0.01）.The increase of endotoxin in children infected with Gram negative bacteria was more obvious.Conclusions Joint detection of endotoxin and CRP in plasma can be one of the fast and sensitive diagnosis methods for identifying Gram negative bacteria and Gram positive bacteria infection in sepsis.

关 键 词：儿童 脓毒症 内毒素 C-反应蛋白 血培养 

分 类 号：R446.11[医药卫生—诊断学]