急性脑梗死并发多器官功能障碍综合征临床分析  被引量:7

The multiple factors in ACI patients with different MODS scores

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作  者:张学敏[1] 谢娟[1] 诸卫英[1] 龙威[1] 李晋峰[1] 段磊[1] 

机构地区:[1]复旦大学附属上海市第五人民医院急诊内科,200240

出  处:《中国综合临床》2012年第5期497-500,共4页Clinical Medicine of China

摘  要:目的探讨急性脑梗死并发多器官功能障碍综合征(MODS)患者与未并发患者在年龄等因素上是否有差异,比较不同MODS评分组之间在年龄等因素间的差异。方法收集157例急性脑梗死患者,分为非MODS组(未并发MODS组)与MODS组,其中MODS组根据评分结果分为4组,分别为1-6分组、7~12分组、13~18分组、≥19分组。分别检测降钙素原(PCT)、C反应蛋白(CRP)、计算出美国国立卫生研究所脑卒中评分(NHISS评分)、急性生理学及慢性健康状况评价(APACHE11评分)、洼田饮水试验评分,比较各组患者在年龄、性别PCT、CRP、NHISS评分、APACHEII评分、洼田饮水试验评分及呼吸支持率、进食率、病死率上的差异。结果非MODS组与MODS组比较,年龄分别为(72.11±16.41)、(77.88±17.67)岁(t=2.451,P〈0.05),男女性别比分别为57/38、34/28(X^2=0.414,P〉0.05),PCT评分为(1.83±0.51)、(2.98±0.71)分(t=4.384,P〈0.01),CRP为(12.53±7.12)、(69.89±43.83)mg/L(t=17.425,P〈0.01),NHISS评分为(9.38±5.24)、(21.35±7.47)分(t=8.317,P〈0.01),APACHEII评分为(11.63±4.22)、(30.92±7.80)分(t=9.476,P〈0.01),洼田饮水试验评分为(2.36±0.98)、(3.88±1.09)分(t=4.23,P〈0.01),呼吸支持为2例(2.1%)、27例(43.5%)(x2=46.213,P〈0.01),进食为91例(95.8%)、41例(66.1%)(x2=24.652,P〈0.01),病死率为4.2%(4/95)、43.5%(27/62)(x2=36.636,P〈0.01)。MODS4组间两两比较,在PCT、CRP、NHISS评分、APACHE评分、洼田饮水试验评分及呼吸支持率、进食率、病死率上差异均有统计学意义(P均〈0.05);1—6分组与其他3组在发病年龄上差异均有统计学意义(P均〈0.05)。结论急性脑梗死并发MODS患者,NODObjective To investigate the differences of multiple factors in acute cerebral infarction (ACI)patients with and without multiple organ dysfunction syndrome (MODS), as well as in ACI patients in different MODS score groups. Methods One hundred and fifty-seven ACI patients were divided into non-MODS group( without concurrent MODS group)and MODS group. The MODS group patients were further divided into four subgroups according to the scores, including 1 -6points ,7 - 12 points, 13 - 18 points and points over 19. All patients were measured for procalcitonin (PCT)and C-reactive protein (CRP). The National Institutes of Health stroke score( NHISS score) , acute physiology and chronic health evaluation( APACHE Ⅱ score)and Watian water test score were calculated. The differences in age, gender, PCT, CRP, NHISS score, APACHE Ⅱ score, Watian water score,breathing support rate, eating rate and mortality rate between the two groups were compared. Results Non-MODS group, compared with the MODS group, was significantly younger ([ 72. 11 ± 16.41 1 years vs. [77.88± 17.67] years,t =2. 451 ,P 〈0. 05) ,and the difference in the ratio of male to female between groups was not significant(57/38 vs. 34/28 ,X2 = 0. 414 ,P 〉 0. 05 ). Differed from MODS group, non-MODS group had significant lower PCT value ( 1.83 + 0. 51 vs. 2. 98± 0.71, P 〈 0. 01 ), CRP value ( [ 12. 53 ± 7.12 ] mg/L vs. [ 69. 89 ± 43.83] mg/L,P 〈 0.01 ) , NHISS score (9. 38± 5.24 vs. 21.35± 7.47,P 〈 0. 01 ) , APACHE Ⅱ score ( 11.63 ± 4. 22 vs. 30. 92 ± 7.80, P 〈 0. 01 ), Watian water score ( 2. 36± 0. 98 vs. 3.88± 1.09, P 〈 0. 01 ), breathing support rate ( 2. 1% vs. 43.5 %, P 〈 0. 01 ) and mortality rate ( 4. 2% vs. 43.5 %, P 〈 0. 01 ), but had remarkable higher eating rate (95.8 % vs. 66. 1% , P 〈 0. 01 ). Pairwised comparison among the four MODS score groups, the PCT, CRP, NHISS score, APACHE score, Watian water test, breathing support rate and mortality rate

关 键 词:脑梗死 多器官功能障碍综合征 

分 类 号:R459.7[医药卫生—急诊医学]

 

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