二巯基丙磺酸钠解救急性四次甲基二砜四胺中毒的临床观察  

A clinical study on Na-DMPS in the emergency treatment of acute tetramine intoxication

作　　者：应斌宇[1] 陈振洲[2] 陈志康[3] 张素勤[1] 林巍[1] 

机构地区：[1]浙江省温州医学院附属第二医院急诊科,325027 [2]温州市公安局毒理实验室 [3]温州医学院药理教研室

出　　处：《中华内科杂志》2000年第2期100-102,共3页Chinese Journal of Internal Medicine

摘　　要：目的　探索急性毒鼠强 (四次甲基二砜四胺 )中毒 (ATI)的临床特效解毒方法。方法应用二巯基丙磺酸钠 (Na DMPS)解救ATI 11例 (次 )患者进行疗效总结 ,并与既往常规治疗的 5例患者进行比较。结果　治疗组获得满意疗效 :无一例死亡 ,预后佳 ,Na DMPS解毒作用显著 ;而对照组 5例死亡 4例 ,1例遗留有严重痴呆症。结论　Na DMPS对ATI具有特效解毒作用 ,值得临床推广应用。Objective To find the clinical specific antidotal treatment of acute tetramine intexication (ATI) Methods The therapeutic effects of sodium dimercaptopropan (Na DMPS) were observed in 11 ATI patients and the results were compared with those of 5 cases treated with traditional methods Results All the cases treated with Na DMPS got good outcome and no case died, while 4 cases in the control group died and in the remaining one severe dementia was left over Conclusion It is suggested that Na DMPS may be a specific remedy for ATI and the therapeutic effects are reliable clinically

关 键 词：二巯基丙磺酸钠 鼠药中毒 毒鼠强 急救 

分 类 号：R595.4[医药卫生—内科学]