老年肝硬化60例临床分析  

Clinical analysis of characteristics of 60 elderly cases with cirrhosis

作　　者：郑成芳[1] 

机构地区：[1]海南省儋州市第一人民医院,海南儋州571700

出　　处：《现代预防医学》2012年第9期2368-2370,共3页Modern Preventive Medicine

摘　　要：目的探讨老年肝硬化的临床特点,分析老年肝硬化的发病原因。方法采用回顾性分析,对60例老年肝硬化与146例非老年肝硬化的临床资料进行对比分析。结果老年组患者黄疸、腹水的发生率分别是76.5%和82%,非老年组为61.2%和63%(P﹤0.05)。老年组Child分级A、B、C级分别为15.5%、53.1%和31.2%,非老年组分别为45.1%、38.2%和16.9%(P﹤0.05)。老年组电解质紊乱、感染、上消化道出血、肝性脑病的发生率分别为59.3%、65.8%、57.1%和62.8%。老年组肝硬化和非老年组肝硬化患者病因分析,两组患者比较存在明显差异性(P﹤0.05)。结论老年肝硬化患者黄疸、腹水、感染、上消化道出血、肝性脑病等并发症的发生率高,转氨酶等反映肝脏炎症的指标升高相对不明显;老年肝硬化患者HBV感染率、原发性胆汁性肝硬化及酒精性肝硬化发生率明显低于非老年组患者,而病因不明肝硬化的发生率高于非老年肝硬化患者。OBJECTIVE To investigate the clinical features and the etiology of elderly cirrhosis.METHODS 60 elderly patients and 146 non-elderly patients with liver cirrhosis were retrospective analyzed.RESULTS Of elderly patients,jaundice and ascites incidence rates were 76.5% and 82%.Of non-elderly group the rates were 61.2% and 63%（P﹤0.05）.A,B,C grades of Child classification of elderly group were 15.5%,53.1% and 31.2%,and of non-elderly group they were 45.1%,38.2% and 16.9%（P﹤0.05）.The rats of electrolyte imbalance,infection,upper gastrointestinal bleeding,and hepatic encephalopathy of elderly patients were 59.3%,65.8%,57.1% and 62.8%.Elderly group and non-elderly group had obvious differences（P﹤0.05）in etiology of cirrhosis.CONCLUSION Elderly patients with liver cirrhosis have the high incidences of jaundice,ascites,infection,upper gastrointestinal bleeding,hepatic encephalopathy and other complications,transaminases and other indicators that reflect theinflammation of the liver don＇t increase obviously;the rates of HBV infection,primary biliary cirrhosis and alcoholic cirrhosis in elderly patients with cirrhosisare are significantly lower than non-elderly patients,and the rate of unknown etiology of cirrhosis is higher than non-elderly patients with cirrhosis.

关 键 词：肝硬化 病因 临床特点 

分 类 号：R657.31[医药卫生—外科学]