盐酸二甲胺四环素软膏治疗牙周病的临床疗效分析  

Clinical analysis of minocycline hydrochloride ointment in the treatment of periodontal disease

作　　者：李惠玲 

机构地区：[1]青海省大学附属医院口腔科,青海西宁810001

出　　处：《现代预防医学》2012年第9期2387-2388,共2页Modern Preventive Medicine

摘　　要：目的探究盐酸二甲胺四环素软膏治疗牙周病的临床疗效。方法选择某院2010年1月～2011年6月收治的50例患者,共计72颗患牙,对所有患者行日本SUNSTAR INC株式会社生产的派力奥牙科盐酸二甲胺四环素软膏治疗,观察临床症状治疗效果、牙周袋深度、牙齿松动度、龈沟出血指数等临床指数变化。结果治疗1个月后的牙龈炎症、牙周脓肿、溢脓、牙齿松动上疗效显著。龈沟出血指数、牙周指数明显下降,同时牙周疾病中牙周炎、牙周脓肿、智齿冠周炎的临床疗效显著,临床疗效有效率为97.2%。结论派力奥牙科盐酸二甲胺四环素软膏是目前治疗牙周疾病的首选治疗措施,可以有效抑制牙周菌斑,抑制宿主反应,其疗效作用强,不易产生耐药性,且副作用小,值得在临床上应用于推广。OBJECTIVE To explore the clinical efficacy of minocycline hydrochloride ointment for treatment of periodontal disease.METHODS From January 2010-June 2011,50 patients were treated in our hospital,a total of 72 teeth,all patients were treated with minocycline hydrochloride ointment produced by SUNSTAR INC Corporation of Japan Dental Palio.The clinical symptoms,periodontal pocket depth,tooth mobility,gingival sulcus bleeding index and other clinical indices changes were observed.RESULTS After one month,the effect on gingival inflammation,periodontal abscess,septic overflow was significant.Sulcus bleeding index,periodontal index were significantly decreased,while in periodontal disease,clinical effects on periodontitis,periodontal abscess,pericoronitis of wisdom teeth were significant,the effective rate was 97.2%.CONCLUSION Dental Palio minocycline hydrochloride ointment is the first choice for treatment of periodontal disease,periodontal plaque can inhibit,suppress the host response,its effect is stronger,difficult to generate resistance,and less side effects,which should be used in clinical practice promotion.

关 键 词：盐酸二甲胺四环素 牙周病 临床疗效 

分 类 号：R961[医药卫生—药理学]