Afinion AS100床旁糖化血红蛋白分析仪测试准确性评估  

Accuracy evaluation of Afinion AS100 hemoglobin A1c analyzer in point-to-care testing

作　　者：李津[1] 邓洪容[1] 杨黛稚[1] 严晋华[1] 石一鸣[1] 邢晓欢[1] 翁建平[1] 

机构地区：[1]中山大学附属第三医院内分泌与代谢病学科,广州510630

出　　处：《广东医学》2012年第8期1111-1113,共3页Guangdong Medical Journal

基　　金：广东省科技计划项目(编号:2010B031500008);广东省医学科研基金资助项目(编号:B2010096);中央高校基本科研业务专项资金(2009年中山大学青年教师培养项目);中山大学临床医学研究5010计划资助项目(编号:2007030)

摘　　要：目的评估一种新型床旁糖化血红蛋白(HbA1C)测定仪器测试的准确性。方法采集70例糖尿病患者和12例非糖尿病志愿者的血标本,分别用1台Afinion AS100床旁HbA1C分析仪(新型床旁仪器)和2台Bio-Rad D10仪器(临床常规检测仪器)测定HbA1C(2～8℃冷藏7 d前后),对比其差异。结果 3台仪器测得HbA1C值的差异无统计学意义(P>0.05);3台仪器再检测冷藏后标本测得值差异均无统计学意义(P>0.05)。结论床旁HbA1C测定仪器(Afinion AS100床旁HbA1C分析仪)的准确性和可靠性与临床常用仪器相似。Objective To evaluate the accuracy of a new kind of point-of-care Hemoglobin A1c（HbA1C） testing analyzer.Methods Seventy diabetic patients and 12 health volunteers were enrolled.HbA1C was assessed with the same Afinion AS100 Analyzer（point-of-care testing,boronate affinity method） and 2 Bio-Rad D10 Analyzers（ion-exchange high performance liquid chromatography method）.Moreover,the HbA1C was re-assessed with the same analyzers after whole blood specimens were refrigerated in 2~8℃ for 7 days.Results There was no significant difference in results of HbA1C among 3 analyzers（P0.05）,neither after refrigeration（P0.05）.Conclusion Afinion AS Analyzer provides similar accuracy and reliability with commonly used analyzer in clinical laboratory.

关 键 词：糖尿病 糖化血红蛋白 床旁检测 

分 类 号：R587.1[医药卫生—内分泌]