甲氟喹抗血吸虫及其他蠕虫作用的研究进展  

Study Progress on Mefloquine against Schistosomes and other Helminths

作　　者：肖树华[1] 薛剑[1] 

机构地区：[1]中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾,血吸虫病和丝虫病合作中心,上海200025

出　　处：《中国寄生虫学与寄生虫病杂志》2012年第2期131-138,145,共9页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：近年来抗疟药甲氟喹,一种氨基乙醇化合物,被发现具有很强的抗血吸虫作用,其特点是对不同发育期的血吸虫童虫和成虫的杀灭作用相仿。本文对近3年有关甲氟喹抗血吸虫和其他蠕虫的实验研究进展进行综述。In recent years,antimalarial drug mefloquine,an amino alcohol compound,has been found to exhibit potential effect against schistosomes.The feature of antischistosomal properties of mefloquine is that the drug possesses similar killing effect against various development stages of juvenile and adult schistosomes.This paper summarizes the recent three years′ progress in experimental studies of mefloquine against schistosomes and other helminthes.

关 键 词：甲氟喹 氨基乙醇化合物 曼氏血吸虫 日本血吸虫 吸虫 多房棘球蚴绦虫 吡喹酮 

分 类 号：R978.613[医药卫生—药品]