宫腔内供精人工授精结局影响因素分析  

Analysis on the outcome of intrauterine artificial insemination with donor's sperm

作　　者：秘祖霞[1] 徐雯[1] 卢伟英[1] 张宇[1] 马燕琳[1] 

机构地区：[1]海南医学院附属医院,海南海口570102

出　　处：《海南医学》2012年第9期9-12,共4页Hainan Medical Journal

基　　金：海南省卫生厅项目(编号:琼卫-2010-42)

摘　　要：目的探讨多种因素对宫腔内供精人工授精(AID-IUI)治疗结局的影响。方法回顾性分析在本中心实施的345个AID-IUI治疗周期,对AID-IUI成功率与女方年龄、治疗周期数等因素的关系进行χ2检验及非条件逐步Logistic回归分析。结果 345个AID-IUI周期,周期临床妊娠率为24.1%。χ2检验显示年龄、不孕年限等因素对AID-IUI结局的影响无统计学意义(P>0.05);Logistic回归分析显示助孕周期次数是影响AID-IUI周期临床妊娠率的危险因素(P<0.01),2次组和≥3次组的OR值分别为6.78[95%CI(2.75～16.71)]及2.87[95%CI(1.12～7.36)]。结论助孕周期次数是影响AID-IUI周期临床妊娠率的重要因素。Objective To analyze the parameters affecting the pregnancy rate in intrauterine artificial insemination with donor's sperm (AID-IUI).Methods A total of 345 AID-IUI cycles in our center were selected.Chi-square test and multiple unconditional logistic regression were performed.Results The pregnancy rate of 345 AID-IUI cycles were 24.1%.The pregnancy outcome showed no statistically significant difference between the groups of different age and duration of infertility (P>0.05).Multivariable stepwise logistic regression model revealed that the number of AID-IUI cycles was a risk factor that affected the pregnancy rate of per cycle.The OR value for 2 cycles group and 3 cycles group were 6.78 [95%CI(2.75~16.71)] and 2.87[95%CI(1.12~7.36)],respectively.Conclusion The number of AID-IUI cycles was one of the most important factors affecting the pregnancy rate of per cycle.

关 键 词：供精人工授精 无精子症 临床妊娠率 

分 类 号：R715[医药卫生—妇产科学]