冠心宁注射液不良反应报告分析  

Adverse reaction reports of guanxinning injection

作　　者：吴文[1] 李磊[1] 尹克鑫[1] 

机构地区：[1]安徽省合肥市第一人民医院药学部,安徽合肥230061

出　　处：《安徽医药》2012年第4期552-553,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨2006年～2010年我院冠心宁注射液不良反应(ADR)发生的一般规律和特点,为临床合理用药提供参考。方法采用回顾性研究方法对该院2006年～2010年冠心宁注射液ADR临床表现及相关因素进行统计分析。结果有效ADR报表18例,发生ADR的患者年龄在60岁以上有11例(61.11%),ADR发生时间1 h内5例(27.78%),超剂量用药15例(83.33%),ADR临床表现以皮肤及其附件损害为主,其次为神经系统损害。结论临床医师、药师应重视冠心宁注射液的不良反应,坚持合理用药。Objective To study adverse reactions（ADR） cases of Guanxinning injection which occurred in Hefei First People＇s Hospital from 2006 to 2010.Methods Clinical manifestations and related factors of Guanxinning injection ADR reports in Hefei First People＇s Hospital from 2006 to 2010 were analyzed and summarized retrospectively.Results A total of 18 cases of valid ADR reports,the patients of 11 cases（61.11%） were above 60 years old.5 cases（27.78%） happened in 1h and 15 cases（83.33%） were overdosed.The clinical manifestations of damage were mainly to skin and its appendages,followed by the nervous system.Conclusion The rational use of guanxinning injection could be improved by effective ADR monitoring.

关 键 词：冠心宁注射液 不良反应 

分 类 号：R286[医药卫生—中药学]