长期饲喂高铜饲粮对猪生长的影响及其机理探讨  

Growth response of pigs fed pharmacolic level of copper diet and approach of the mechanism:

作　　者：许梓荣 周勃 王敏奇 奚刚 

机构地区：[1]农业部饲料与动物营养重点开放实验室

出　　处：《浙江农业学报》2000年第2期55-60,共6页Acta Agriculturae Zhejiangensis

基　　金：国家自然科学基金项目 !(3970 0 1 0 3)资助

摘　　要：选用 4 8头“杜长大”生长猪 ,分为两组 (每组 3个重复 ) ,分别饲喂添加 5mg/kg和 2 4 0mg/kg铜的相同饲粮 ,进行为期 70d的饲养试验 ,然后屠宰取样 ,研究长期添加高剂量铜对猪生长的影响及其作用机理。全期饲养试验结果表明 ,添加高剂量铜使日增重提高 10 94 % (P <0 0 1) ,料重比降低 7 16 % (P <0 0 5)。样品分析结果显示 :添加高剂量铜使血清、胆汁和脑的铜含量分别提高2 5 58% (P <0 0 1) ,186 45% (P <0 0 1)和 2 1 35% (P <0 0 5) ,血清中生长激素浓度提高了 77 0 4 %(P <0 0 1) ,血清铜蓝蛋白和肝脏SOD活性分别提高 4 2 58% (P <0 0 1)和 2 5 6 6 % (P <0 0 1) ,腺垂体中cAMP的含量升高 2 6 98% (P <0 0 1)。但长期添加高铜导致T3浓度下降 2 8 6 5% (P <0 0 5) ,血清总蛋白、白蛋白、胆固醇浓度分别下降 10 0 4 % (P <0 0 5) ,10 2 8% (P <0 0 1)和 16 0 3% (P <0 0 1) ,甘油三酯含量和GPT活性分别上升 83 0 6 % (P <0 0 1)和 2 1 44 % (P <0 0 5)Forty eight crossbred pigs (Duroc×landrace×Yorkshire) were used to determine growth response of pigs fed pharmacolic level of copper diet and approach to the mechanism.The results of the feeding trial showed that high level supplementation of copper improved pigs growth performance,as ADG increased by 10.94%( P <0 01) and F/G decreased by 7.16% ( P <0.05).The analysis of samples showed that high copper increased copper concentrations in serum,bile and brain respectively by 25.58% ( P <0 01),186.45%( P <0 01) and 21.35%( P <0 05),increased GH concentration by 77.04% ( P <0.01),enhanced caeruloplasmin activity in serum and SOD in liver by 42.58% ( P <0.01) and 25.66% ( P <0.01),elevated cAMP concentration in anterion pituitay by 26.98%( P <0.01).But supplemental copper decreased T 3 concentration by 28.65% ( P <0.05),decreased concentrations of TP,ALB and CHL respectively by 10.04% ( P <0.05),10.28% ( P <0 01),and 16.03% ( P <0.01),increased TG 3 concentration and GPT activity by 83.06% ( P <0.01) and 21.44% ( P <0.05).

关 键 词：铜 猪 生长 激素 饲料 机理 

分 类 号：S828.5[农业科学—畜牧学]