防治糖尿病药物筛选方法的探讨  

Method Research of Prevention and Treatment of Diabetes Drug Screening

作　　者：梁雪[1] 苗明三[1] 

机构地区：[1]河南中医学院,河南郑州450008

出　　处：《中医学报》2012年第5期600-603,共4页Acta Chinese Medicine

基　　金：河南省科技攻关项目(编号:112102310076);河南省国际合作项目(编号:104300510011);郑州市科技领军人才项目(编号:0910SGYS3527);河南省高校科技创新团队项目(编号:2012IRTSTHN011)

摘　　要：目的:探讨防治糖尿病药物筛选的方法。方法:通过整合各研究文献对糖尿病病因病机的认识,综述近10a来防治糖尿病药物的研究进展,总结出药物干预糖尿病的各种途径。结果:利用现有的细胞模型和动物模型进行降糖药物筛选的方法,有进一步完善的必要。结论:利用现有的细胞模型和糖尿病动物模型,探讨药物防治糖尿病的作用特点,为进一步筛选糖尿病治疗药物和开发新药提供思路。Objective：To explore the screening method of prevention and treatment of diabetes drug screening.Methods：through the integration of the research literature on diabetic knowledge of etiology and pathogenesis,summary the prevention and treatment progress on drug research of the last ten years diabetes,summed up the various ways of drug intervention in diabetic.Results：Using the existing cell model and an animal model of antidiabetic drug screening methods,the need to further improve.Conclusion：The use of existing cell model and animal models of diabetes,diabetes prevention and cure effect of drugs,for further screening of drug treatment of diabetes mellitus and the development of new drugs to provide train of thought.

关 键 词：糖尿病治疗 药物干预 筛选 

分 类 号：R285.5[医药卫生—中药学]