二丁酰环磷腺苷钙预防甲状腺瘤切除术颈丛神经阻滞麻醉时血压升高的效果  

Prevention of intra-operative high blood pressure caused by cervical plexus block using calcium dibutyryladenosine cyclophosphate

作　　者：董龙禹[1] 李江伟[1] 吴明毅[1] 窦林彬[1] 郭玉洁[1] 孙玉明[1] 褚文彦[1] 

机构地区：[1]武警山东总队医院麻醉科,济南250014

出　　处：《武警医学》2012年第4期329-331,共3页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的探讨二丁酰环磷腺苷钙用于预防甲状腺瘤切除术颈丛神经阻滞麻醉时血压升高的效果。方法甲状腺瘤切除术患者80例,ASAⅠ或Ⅱ级,40～70岁,随机分为观察组与对照组,每组40例,均采用0.375%罗哌卡因30 ml颈丛神经阻滞麻醉(患侧颈深丛加双侧颈浅丛,每点10 ml)。观察组二丁酰环磷腺苷钙40 mg加入复方乳酸钠林格液500 ml,输注速度8 ml/(kg.h);对照组单纯输注复方乳酸钠林格液。观察记录患者血压、心率变化。结果观察组与对照组的血压增高发生率分别为2.5%、95%,心动过速发生率分别为5%、90%(P<0.01)。结论二丁酰环磷腺苷钙可预防甲状腺瘤切除术颈丛神经阻滞麻醉时血压增高及心动过速。Objective To study the feasibility of calcium dibutyryladenosine cyclophosphate being used to prevent intra-operative high blood pressure caused by cervical plexus block（CPB）.Methods Eighty patients,ASAⅠorⅡ,aged 40 to 70 and scheduled for thyroma resection,were randomly divided into observation group and control group of 40 patients each.0.375% ropivacaine 30 ml CPB was used in both groups.In the observation group 40 mg calcium dibutyryladenosine cyclophosphate was added into Ringer lactated solution 500 ml at an infusion rate of 8 ml /（kg·h） while in the control group only Ringer lactated solution was infused at the same rate.The blood pressure and heart rate changes were observed.Results In the two groups,the incidence of intra-operative high blood pressure was 2.5%（observation group） and 95%（control group）,and that of tachycardia was 5%（observation group） and 90%（control group）,respectively.There was statistically significant difference between the two groups（P0.01） Conclusions Calcium dibutyryladenosine cyclophosphate effectively prevents intra-operative high blood pressure and tachycardia caused by CPB.

关 键 词：二丁酰环磷腺苷钙 颈丛神经阻滞麻醉 血压 心动过速 

分 类 号：R614.4[医药卫生—麻醉学]