防芷鼻炎片中芍药苷含量测定方法的优化  

Determination of Paeoniflorin in Fangzhi Biyan Tablets by HPLC

作　　者：黄杰芳 

机构地区：[1]广州中一药业有限公司,510530

出　　处：《中国现代药物应用》2012年第8期16-17,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨HPLC法测定防芷鼻炎片中芍药苷含量的优化条件。方法采用HPLC法测定芍药苷含量。结果芍药苷在0.0346～0.519μg范围内线性关系良好,精密度试验RSD为2.7%(n=6),加样回收率为102.5%,RSD为1.8%。结论方法重现性好、准确,能有效控制该制剂的质量。Objective To improve a HPLC method for determination of Fangzhi Biyan Tablets.Methods The content of Paeoniflorin in Fangzhi Biyan Tablets was identified by HPLC.Results Paeoniflorin showed a good linear relationship of 0.0346～0.519 μg.The RSD of measurement precision test was 2.7%（n=6）.The recovery was 102.5%,（RSD=1.8%）.Conclusion The method is accurate,and reproducible and can be used for the quality control of Fangzhi Biyan Tablets.

关 键 词：防芷鼻炎片 芍药苷 HPLC含量测定 

分 类 号：R286[医药卫生—中药学]