毛母质瘤临床与病理回顾性分析  

A RETROSPECTIVE STUDY OF CLINIAL AND PATHOLOGICAL FEATURES IN PILOMATRICOMA

作　　者：韩建文[1] 王晓彦[1] 李东霞[1] 乌日娜[1] 

机构地区：[1]内蒙古医学院附属医院皮肤科,内蒙古呼和浩特010050

出　　处：《内蒙古医学院学报》2012年第2期108-112,共5页Acta Academiae Medicinae Neimongol

基　　金：国家自然科学基金<银屑病与系统性红斑狼疮共同易感基因TNIP1和TNFAIP3基因精细定位研究>(编号31160192)资助

摘　　要：目的:研究毛母质瘤临床、病理特征。方法:回顾分析43例毛母质瘤临床资料和组织病理检查结果。结果:多数病人为单发皮损(占95.35%);发病年龄30岁以下占86.05%,男女比例1∶1.39;好发于面颈部、上肢,肿瘤直径0.3～2.5cm。临床与病理诊断的符合率为11.63%。毛母质瘤4种特征性病理改变(影细胞、嗜碱细胞、过渡细胞和钙化)的发生率分别为100%、68.89%、48.89%和24.44%。结论:毛母质瘤是一种缓慢生长的良性皮肤肿瘤,临床表现多样化,易误诊,临床上需要与皮脂腺囊肿、皮肤纤维瘤、表皮囊肿、血管瘤等疾病相鉴别。因此发生于面颈部、上肢的硬性结节应当完整手术切除后行组织病理检查以明确诊断。Objective：To investigate the clinical and pathological features of pilomatricoma. Meth- od：Clinical manifestations and pathological findings of 43 patients with pilomatrieoma were retrospectively investigated. Result：Single lesion occurred in most patients （95.35 % ）and 86.05 % of them were younger than 30 years. The male - female ratio was 1 ： 1.39. The lesions which sizes ranged from 0. 3 to 2.5cm were commonly emerged in the cheeks, neck, and upper extremity. The correct diagnosis was made preoperatively in 5 patients （ 11.63 % ）. The presence of ghost cells, basaloid cells, transition cells and calcification in slide was 100% , 68. 89% , 48.89% and 24.44% , respectively. Conclusion： Pi- lomatricoma is a slowly growing benign cutaneous tumour. The manifestation is diversed and easily mis- diagnosed. The differential diagnoses including atheromatous cyst, dermatofibroma, epidermal cyst and angioma are needed in clinic. Biopsy after complete surgical excision is recommended for nodules on head, neck and upper extremity.

关 键 词：毛母质瘤 临床表现 组织病理 

分 类 号：R758.7[医药卫生—皮肤病学与性病学]