应用生物电阻抗法评估维持性血液透析患者体液状况的探讨  

Assessment of Body Fluid Status in Patients with Maintenance Hemodialysis by Bioelectrical Impedance Analysis

作　　者：刘俊成[1] 程骏章[1] 胡波[2] 朱晓华[1] 莫继安[1] 艾俊英[1] 胡守亮[1] 袁凡丽[1] 陈蓉[1] 

机构地区：[1]长江大学附属第一医院肾内科,荆州434000 [2]长江大学附属第一医院检验科,荆州434000

出　　处：《临床肾脏病杂志》2012年第4期168-170,共3页Journal Of Clinical Nephrology

摘　　要：目的探讨生物电阻抗法（bioeleetricalimpedanceanalysis，BIA）对维持性血液透析（MHD）患者体液状况的临床价值。方法选择行MHD的稳定患者93例（实验组）及健康志愿者109例（对照组），并按性别分组。实验组按BIA检测时间分为血液透析前组（A组）、血液透析后组（B组）及下次血液透析前组（C组）。应用生物电阻抗仪，测算各组的细胞外液占体质量的百分比（ECV％）、细胞内液占体质量的百分比（ICV％）、身体水分总量占体质量的百分比（TBW％）、细胞外液／细胞内液（ECV／ICV）及浮肿指数（ECW／TBW）。比较各组间相关指标的差异。结果①在年龄相当时，女性体质量、身高均以实验组低。②对照组、A组、B组和3组之间的ECV％、ECV／ICV及ECW／TBW的差异均有统计学意义（P〈O．05）；无性别差异。实验组女性ICV％、TBW％大于对照组。③ECV％、ECV／ICV、ECW／TBW以B组最小。结论MHD患者存在营养不良，女性患者更常见。ECV％、ECV／ICV、ECW／TBW可作为监测MHD患者体液状况的指标。BIA在评估MHD患者体液状况方面值得进一步研究。Objective To explore the clinical value of bioelectrical impedance analysis for evaluating body fluid status in maintenance hemodialysis patients Methods Ninety-three cases of stable patients （ex- perimental group） undergoing maintenance hemodialysis and 109 cases of the control group were recruited, and grouped by gender. The experimental group was subdivided into pre-hemodialysis subgroup （A）, post- hemodialysis subgroup （B） and the next pre-hemodialysis subgroup （C） by BIA detection period. ECV%, ICV%, TBW%, ECV/ICV and ECW/TBW in each group were estimated. The difference in the related in- dicators among groups was observed. Results （1） In age-matched, female body mass and height were re- duced in the experimental group~ （2） There was significant difference in ECVM, ECV/ICV and ECW/TBW among control group, subgroup A and subgroup B （P（0. 05）. There was no difference between sexes. ICV~ and TBWM in the females of the experimental group were larger than the control group; （3） ECV%, ECV/ICV and ECW/TBW were the smallest in the subgroup t3. Conclusions There exists malnu- trition in patients undergoing maintenance hemodialysis, more common in females ECV%, ECV/ICV and ECW/TBW can be used as indicators for monitoring fluid status in MHD patients. Assessment of body fluid status by BIA in MHD patients deserves further study.

关 键 词：血液透析 体液 技术评估 生物医学 

分 类 号：R459.5[医药卫生—治疗学]