基于周仲瑛教授大样本“瘀热”病案数据挖掘分析研究报告  

Data mining analysis of medical record of large samples 'blood stasis and heat' raised by professor ZHOU Zhong-ying

作　　者：叶放[1] 李国春[1] 沈波[1] 金路[1] 周学平[1] 吴勉华[1] 

机构地区：[1]南京中医药大学国家中医药管理局中医瘀热病机重点研究室,南京210029

出　　处：《中华中医药杂志》2012年第5期1294-1297,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家重点基础研究发展计划(973计划)(No.2006CB504807);江苏名医效方研究开发与评价业务建设(No.BM2009903-KF11)~~

摘　　要：目的:通过大样本病案分析总结、整理国医大师周仲瑛教授从"瘀热"论治内科难治性疾病的临床经验。方法:从周仲瑛教授经治的6 005例临床病案中选择"瘀热"病案1 024例,建立"瘀热"病案数据库,从瘀热相关四诊信息、病机证素、方药3个方面进行总结分析。结果:①"瘀热"病机在临床病案中出现率为20.8%,涉及内外妇儿等科160种疾病;②瘀热病机信息表征依次是口干、便干、乏力、尿黄、胁痛、神疲、腹胀、头昏、关节不适等(均超过11%);③涉及病理因素以热、瘀、虚、瘀热为最多(均超过50%),病位主要在肝、肾,涉及五脏六腑;④凉血化瘀法的代表方是犀角地黄汤、桃仁承气汤、抵当汤、白薇煎,常与化湿、滋阴、益气、清热等方药配伍使用。结论:"瘀热"可见于临床多种疑难病症过程中,临床信息表征具有一定规律可循,常与其他病机兼夹复合为患,且瘀热每多兼阴虚。Objective： Exploring the clinical experience of refractory disease from large sample of ＇blood stasis and heat＇ medical record by Chinese medicine Master Professor ZHOU Zhong-ying. Methods： 1024 cases of ＂blood stasis and heat＂ medical record were selected from 6005 cases treated by Professor ZHOU Zhong-ying, blood stasis and heat medical record database was established. Four diagnostic information, pathogenesis elements, herbs were analyzed. Results： ①incidence of blood stasis and heat pathogenesis was 20.1%, 160 kinds of diseases of internal medicine, surgery, gynecology, paediatrics were involved. ② pathogenesis of blood stasis and heat is characterized by mouth dry, dry stool, fatigue, dark urine, hypochondriac pain, abdomen bloating, dizziness, joint discomfort, etc. （more than 11%）. ③pathological factors is characterized by heat, blood stasis, blood stasis and heat （more than 50%）, disease location, mainly by liver, kidney, all internal organs involved. ④recipe of cooling blood and resolving stasis is characterized by rhino horn Rehmanniae decoction, peach kernel decoction, didang decoction, Bai Wei decoction. Conclusion： Pathogenesis of ＇blood stasis and heat＇ can be presented in many difficult cases, clinical information representation can be found, it may often associated with other complex pathogenesis, such as Yin-deficiency.

关 键 词：瘀热 病机 数据挖掘 周仲瑛 

分 类 号：R249[医药卫生—中医临床基础]