Pine pollen inhibits cell apoptosis-related protein expression in the cerebral cortex of mice with arsenic poisoning  

作　　者：Yanhong Luo Yaodong Wei Taizhong Wang Dongzhu Chen Tiansheng Lu Ruibo Wu Keke Si 

机构地区：[1]Department of Clinical Biochemistry and Molecular Biology, Youjiang Medical College for Nationafities, Baise 533000, Guangxi Zhuang Autonomous Region, China [2]Department of Biochemistry and Molecular Biology, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China [3]Grade 2008, Department of Medical Laboratory Science, Youjiang Medical College for Nationalities, Baise 533000, Guangxi Zhuang Autonomous Region, China

出　　处：《Neural Regeneration Research》2012年第12期896-899,共4页中国神经再生研究（英文版）

基　　金：supported by the Guangxi Bureau of Traditional Chinese Medicine,No.[2009]73;the Department of Science and Technology,Guangxi Zhuang Autonomous Region,No.0640203

摘　　要：Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.Previous studies have demonstrated that pine pollen can inhibit cerebral cortical cell apoptosis in mice with arsenic poisoning. The present study sought to detect the influence of pine pollen on apoptosis-related proteins. Immunohistochemistry, western blotting and enzyme-linked immunosorbent assays were used to measure the levels of apoptosis-related proteins in the cerebral cortex of mice with arsenic poisoning. Results indicated that pine pollen suppressed cell apoptosis in the cerebral cortex of arsenic-poisoned mice by reducing Bax, Bcl-2 protein expression and increasing p53 protein expression.

关 键 词：pine pollen arsenic poisoning APOPTOSIS cerebral cortex neural regeneration 

分 类 号：Q274[生物学—细胞生物学] Q255