孕妇桡动脉血流图对预测子痫前期的临床观察  

Clinical value of the radial artery flow chart for the prediction of pre-eclampsia in pregnant women

作　　者：孙茜[1] 侯艳梅[1] 

机构地区：[1]济南市妇幼保健院妇产科,济南250001

出　　处：《山东大学学报（医学版）》2012年第5期120-123,共4页Journal of Shandong University:Health Sciences

摘　　要：目的探讨孕妇桡动脉血流图的监测在预测子痫前期中的应用价值,以准确识别有高危风险的孕妇,早期预测子痫前期的发生,减少母婴伤害。方法对产前检查无高血压、糖尿病、心、肝、肾等并发症,孕周为16～36周的10 433例孕妇分为预测组(5 223例)和对照组(5 210例)。预测组应用桡动脉血流图进行监测,每4周重复1次,对预测阳性者每2周重复测定并给予干预措施;对照组直到发现子痫前期症状时才给予干预。随访两组患者至分娩结束,对两组患者子痫前期的发生率、发病程度及新生儿体质量进行比较。结果预测组中子痫前期及子痫的发病率分别为11.2%和0.11%,对照组中子痫前期及子痫的发病率分别为13.5%和0.29%(P<0.05);新生儿生长受限率在预测组和对照组中分别为5.11%和7.06%(χ2=15.38,P<0.01);对照组中子痫前期的病情程度明显较预测组重(P<0.05);妊娠期高血压疾病监测系统在不同孕周预测子痫前期的敏感度不同,预测子痫前期的阳性符合率随孕周增加而增加。结论应用妊娠期高血压疾病监测系统及动态桡动脉血流动力学指标的改变早期预测子痫前期,对预测阳性者给予临床指导,可降低其发病率并防止病情发展,改善孕产妇和围产儿的结局。Objective To evaluate the clinical value of the radial artery blood flow for predicting pre-eclampsia in gravidas,and to accurately identify high-risk pregnant women,and to early predict the incidence of pre-eclampsia.Methods Data from 10 433 pregnant women at 16-36 weeks of gestation who were free of hypertension,diabetes mellitus,renal disease,cardiovascular disease and other complications in prenatal screening were analyzed by the case-control study.These pregnant women were randomly divided into the study group and the control group.The pregnant women in the study group were monitored for the radial artery flow chart by the hypertensive disorder in the pregnancy monitoring system.They were examined at 4-week intervals.For the pregnant women positive with hypertensive disorders by the pregnancy monitoring system,the measurement was repeated every 2 weeks and intervention was applied.The pregnant women in the control group were given interventions until pre-eclampsia symptoms appeared.All pregnant women were followed-up until after delivery.The severity and the incidence of pre-eclampsia and Intrauterine Growth Retardation（IUGR） in the two groups were compared.Results The incidences of pre-eclampsia and eclampsia in the study group were 11.2% and 0.11%,while the incidences were 13.5% and 0.29%（P〈0.05） in the control group.The rates of IUGR in the study and control groups were 5.11% and 7.06%（χ2=15.38,P〈0.01）.The severity of pre-eclampsia in the control group was significantly higher compared to the study group（P〈0.05）.The sensitivity of the MP monitoring system in predicting pre-eclampsia was different at different gestational ages,and the rate of the pre-eclampsia positive prediction coincidence increased with the gestational age.Conclusions Applying the pregnancy monitoring system for hypertensive disorders to early predict pre-eclampsia,and giving interventions to pregnant women with positive predictions,can significantly reduce the incidence of pre-eclampsia and prevent the developmen

关 键 词：子痫前期 桡动脉血流图 预测 干预 

分 类 号：R714.245[医药卫生—妇产科学]