2008～2009年江苏省3城市男男性行为人群HIV-1新发感染率调查  

A survey of HIV-1 incidence of men who have sex with men in three cities of Jiangsu province,2008-2009

作　　者：胡海洋[1] 徐晓琴[1] 傅更锋[1] 郭宏雄[1] 闫红静[1] 刘晓燕[1] 管文辉[1] 还锡萍[1] 肖瑶[2] 羊海涛[1] 

机构地区：[1]江苏省疾病预防控制中心性病与艾滋病防制所,江苏南京210009 [2]中国疾病预防控制中心性病艾滋病预防控制中心,国家艾滋病参比实验室,北京100050

出　　处：《南京医科大学学报（自然科学版）》2012年第4期487-490,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省社会发展计划资助(BE2009685);江苏省自然科学基金(BK2009432,BK2009435);江苏省医学重点人才资助(RC2011083,RC2011086,RC2011087)

摘　　要：目的:了解江苏省男男性行为人群(men who have sex with men,MSM)HIV的感染状况,估算HIV在该人群中的新发感染率。方法:对2008～2009年南京、扬州、苏州3城市MSM 3轮调查的3 152份样本,进行HIV-1初筛、复检及确证试验,检出的HIV-1阳性样本,再应用BED HIV-1 IgG捕获酶免疫法(BED-CEIA)检出其中的新发感染样本,进而估算该人群的HIV-1新发感染率。结果:3 152份样本共检出HIV-1阳性样本175份,其中92份被判定为新发感染,南京市3轮调查的HIV-1新发感染率分别为7.05%、5.18%、3.71%,扬州市分别为6.99%、2.39%、12.27%,苏州市分别为6.73%、3.31%、9.84%。结论:HIV-1在江苏省MSM人群中的流行仍处于较高水平,且新发感染状况不容乐观,必须加大防控力度。Objective： To understand HIV infection of men who have sex with men（MSM） in Jangsu province,and to estimate the annual HIV incidence of MSM.Methods：Total 3 152 samples from 3 rounds survey in 3 cities（Nanjing,Yangzhou and Suzhou）among MSM during 2008-2009 were tested to find HIV-1 seropositive samples.HIV-1 seropositive samples were tested with BED HIV-1 IgG capture enzyme immunoassay（BED-CEIA） to find recent HIV-1 infections and to estimate the annual HIV-1 incidence of MSM.Results： There were 175 samples found to be HIV-1 seropositive,and 92 samples confirmed to be recently infected.The annual HIV-1 incidence of 3 rounds survey were 7.05%,5.18% and 3.71% in Nanjing,6.99%,2.39% and 12.27% in Yangzhou,6.73%,3.31% and 9.84% in Suzhou.Conclusion： The prevalence of HIV-1 in MSM in Jiangsu province was still at a high level.Powerful prevention and control effort must be made.

关 键 词：HIV BED-CEIA 新发感染率 男男性行为人群 

分 类 号：R512.91[医药卫生—内科学]