突触可塑性分子机制的相关研究  

Molecular Mechanisms of Synaptic Plasticity Related Research

作　　者：张永杰[1] 唐冬梅[1] 徐桂萍[2] 

机构地区：[1]石河子大学医学院,新疆石河子832000 [2]新疆维吾尔自治区人民医院麻醉科,乌鲁木齐830000

出　　处：《医学综述》2012年第8期1141-1143,共3页Medical Recapitulate

基　　金：新疆维吾尔自治区自然科学基金(2011211A056)

摘　　要：近年来,突触可塑性在学习记忆中所产生的作用一直是人们关注的焦点。突触是神经信息传递的关键部位,突触可塑性被认为是突触形态的改变、新的突触的形成及传递性能的建立,突触可塑性是学习与记忆的细胞分子学基础,其介导了神经兴奋性的传导,对神经元突触可塑性和神经构筑产生了重要影响,因而与学习记忆关系密切。现就突触可塑性分子机制对学习记忆的影响进行综述。In recent years,researchers have paid close attention to the role of synaptic plasticity in learning and memory.Synaptic is a key part of neural information transmission,and synaptic plasticity is considered as synaptic changes,the new synaptic formation and the establishment of transmission performance.Synaptic plasticity is the molecular basis of learning and memory,which mediates the transmission of nerve excitability,and has a major influence on synaptic plasticity of neurons establishment,therefore is closely related to learning and memory.Here is to make a review on the molecular mechanisms of synaptic plasticity in learning and memory.

关 键 词：突触可塑性 长时程增强 学习记忆 机制 

分 类 号：R338[医药卫生—人体生理学]