电纺丝制备纳米纤维及其应用  

Electrospun Nanofibers and Their Applications

作　　者：马贵平[1] 方大为[2] 刘洋[2] 陈洁[2] 聂俊[1] 

机构地区：[1]北京化工大学材料科学与工程学院,北京100029 [2]常州大学材料科学与工程学院,江苏常州213164

出　　处：《材料科学与工程学报》2012年第2期312-323,共12页Journal of Materials Science and Engineering

基　　金：江苏省自然科学基金资助项目(BK2010190);常州市微电子化学材料研发公共技术平台资助项目(CZ2010003)

摘　　要：电纺丝技术是利用高压静电将聚合物或具有粘弹性的溶液制备成纳米级直径纤维的一种加工技术。电纺丝纤维膜由于其高比表面积、良好的生物仿生性能,在生物组织工程支架、药物载释、伤口修复等方面有较高的应用价值。近年来,大量文献报道,通过对电纺丝装置以及纺丝过程参数的改进和优化,制备出功能化和具有特殊结构的纳米纤维材料。本文从电纺丝装置的改进、纺丝过程优化等方面简述了电纺丝技术的进展。概述了电纺丝法制备特殊结构的纳米纤维的方法,及其在生物组织工程、药物载释等方面的应用。Electrospinning is a promising technology to prepare nanofibers from polymer solutions or viscoelastic solutions based on high voltage electrostatic repulsions.Electrospun nanofiber mats have been extensively studied and applied in tissue engineering,drug delivery and wound dressing,due to their amazing properties,such as high surface area to volume ratio,high porosity and excellent biological property.Recently,nanofibers with various functionalities and special nanostructures have been prepared via electrospinning by improving electrospinning devices and optimizing process parameters.This article presents a brief overview on the progress of electrospinning process,optimizing and improvement of electrospinning devices.The approaches to prepare special structure nanofibers were summarized.The recent applications of elecrospun nanofiber mats in biomedical fields such as tissue engineering,drug delivery,wound dressing were also illustrated.

关 键 词：电纺丝 纳米纤维 组织工程 药物载释 

分 类 号：TS102.528[轻工技术与工程—纺织工程]