新鱼腥草素钠结构确证的波谱学研究  

Spectral Study on the Structural Confirmation of Sodium Lauroyl-α-hydroxyethyl Sulfonate

作　　者：兰玉梅[1] 黄红[1] 韩璐[1] 张伶俐[1] 

机构地区：[1]四川大学华西第二医院药剂科,成都610041

出　　处：《中国药房》2012年第19期1777-1779,共3页China Pharmacy

摘　　要：目的:为新鱼腥草素钠的结构确证提供波谱学依据。方法:通过红外光谱(IR)、一维(1H、13C)和二维(1H-1H COSY、HMQC、HMBC)核磁共振光谱(NMR)、质谱(MS)等波谱法研究新鱼腥草素钠的波谱性质。结果:确认了新鱼腥草素钠IR信号峰;归属了NMR中1H、13C信号的化学位移;详细分析了新鱼腥草素钠MS中主要碎片离子的裂解途径。结论:经波谱学研究确证了新鱼腥草素钠的结构。OBJECTIVE：To provide the spectral evidence for the structural identification of sodium lauroyl-α-hydroxyethyl sulfonate.METHODS：The spectral properties of sodium lauroyl-α-hydroxyethyl sulfonate were studied through spectroscopic methods including IR,1D and 2D NMR,and MS spectroscopic techniques.RESULTS：In the paper,the assignment of IR signals and 1H,13C chemical shifts had been completed,and the main cleavage pathways of fragment ions in MS spectrum had also been analyzed in detail.CONCLUSION：The structure of sodium lauroyl-α-hydroxyethyl sulfonate is verified by intensive spectral studies.

关 键 词：新鱼腥草素钠 结构解析 波谱学 

分 类 号：R284.1[医药卫生—中药学] R927[医药卫生—中医学]