MRI在肺癌脑转移瘤诊断和放疗疗效判定中的价值  

MRI in Diagnosis and Evaluation of the Brain Metastatic Tumors from Lungs before and after Radiotherapy

作　　者：田霞[1] 陆紫微[1] 孙琪[1] 谢道海[1] 

机构地区：[1]苏州大学附属第一医院放射科,江苏苏州215006

出　　处：《中国血液流变学杂志》2012年第1期152-155,共4页Chinese Journal of Hemorheology

摘　　要：目的 探讨增强MRI和弥散加权（DWI）在肺癌脑转移瘤诊断和放疗疗效判定中的价值.方法 回顾性分析经病理确诊为肺癌并经临床诊断为脑转移瘤的27例患者,所有病例均行MRI检查,包括T1WI、T2WI、T1WI增强及DWI扫描.结果 与其他序列相比T1WI增强检出率最高.转移瘤实质部分,瘤周水肿区和对侧正常脑实质区三者间ADC值差异显著.转移瘤放疗前后：瘤灶实质区ADC值差异显著,瘤周水肿区ADC值差异无统计学意义.结论 增强T1WI是发现脑转移的最佳序列,DWI和ADC值有助于脑转移瘤的定性诊断和放疗前后疗效评估.Objective To explore the values of contrast-enhanced MR imaging and diffusion-weighted imaging（DWI） of brain metastatic tumors from lung cancer before and after radiation therapy.Methods Twenty- seven patients with brain metastatic tumors from primary lung cancers confirmed by clinical or pathology were examined with routine MR imaging,including T1WI,TEWI and contrast-enhanced T1WI,and DWI.Results Compared with other sequences,contrast-enhanced T^WI had the highest detection rate.There were significant differences among the mean ADC values of tumor solid portion,edema zone and that in the contralateral normal brain（P 〈 0.05）.There was a significant difference in tumor solid portion before and after radiotherapy, but there was no difference in edema zone.Conclusion Contrast-enhanced T1WI is the best sequence for detecting metastatic lesions in brain.The DWI and ADC values take a great role in diagnosis and evaluation of the brain metastatic tumors before and after radiotherapy.

关 键 词：磁共振成像 弥散加权成像 脑转移瘤 放疗 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]