香豆素类荧光增强型Cu^(2+)荧光分子探针  

Fluorescence-enhanced Probe for Cu^(2+) Based on Coumarin

作　　者：马文辉[1,2] 韩宏彦[2] 徐群[2] 夏威[2] 宋波[2] 梁春花[2] 孙丽微[2] 

机构地区：[1]齐齐哈尔大学材料科学与工程学院,黑龙江齐齐哈尔161006 [2]齐齐哈尔大学精细化工黑龙江省普通高校重点实验室,黑龙江齐齐哈尔161006

出　　处：《精细化工》2012年第5期425-428,457,共5页Fine Chemicals

基　　金：黑龙江省普通高等学校青年学术骨干支持计划项目(1152G054);齐齐哈尔市工业攻关计划项目(GYGG2010-05-1)~~

摘　　要：设计合成了含酰肼和亚胺结构的双香豆素类Cu2+荧光分子探针CCu,其结构用1HNMR、IR、HRMS和元素分析进行了表征,并考察了其光谱性能。CCu在常见碱金属离子(K+,Na+)、碱土金属离子(Ca2+,Mg2+)、过渡金属及重金属离子(Cd2+,Ag+,Fe3+,Pb2+,Hg2+,Cr3+,Co2+,Ni2+,Cu2+,Zn2+)中能够专一性地识别Cu2+。滴加Cu2+后引起吸收光谱蓝移38 nm,荧光光谱蓝移17 nm,荧光增强8.2倍,溶液荧光由无色变为蓝色。CCu对pH不敏感具有较低的pKa值(3.32±0.07),可在近中性和弱碱性范围内对Cu2+进行检测。A fluorescent molecular probe CCu for Cu2＋ based on biscoumarin bearing hydrazide and imine unit was designed and synthesized.The structure of CCu was identified by 1HNMR,IR,HRMS and elemental analysis,and the spectral properties of CCu was investigated.CCu exhibited Cu2＋-only sensitivity among metal ions such as alkali（K＋,Na＋）,alkaline earth（Ca2＋,Mg2＋）,and transition metal ions（Cd2＋,Ag＋,Fe3＋,Pb2＋,Hg2＋,Cr3＋,Co2＋,Ni2＋,Cu2＋,Zn2＋）.The addition of Cu2＋ led to a 38 nm blue-shift in absorbance maximum,a 17 nm blue-shift in fluorescence maximum,an 8.2-fold fluorescence enhancement and an obvious fluorescence change from almost colorless to blue.CCu was pH-insensitive,with a low value of pKa（3.32±0.07）,which could be used for Cu2＋ detection in neutral and weakly alkaline pH span.

关 键 词：荧光分子探针 香豆素 CU2+ 荧光增强 功能材料 

分 类 号：O657[理学—分析化学] O625[理学—化学]