舍曲林治疗经前期综合征临床疗效观察  

Clinical Curative Effect of Sertraline in the Treatment of Premenstrual Syndrome

作　　者：刘丽[1] 王嘉悦[1] 高志俊 

机构地区：[1]河北省唐山市第三医院,河北063000 [2]唐山友谊医院心理科

出　　处：《中国健康心理学杂志》2012年第4期524-525,共2页China Journal of Health Psychology

摘　　要：目的探讨舍曲林治疗经前期综合征的疗效。方法采用症状自评量表(SCL-90)和汉密尔顿焦虑量表(HAMA)对57例经前紧张患者进行使用舍曲林治疗前后疗效评定。结果①57例经前期综合征患者使用舍曲林治疗后,SCL-90评定躯体化、抑郁、焦虑及其它因子分较治疗前明显降低,差异具有统计学意义(t分别=9.918,9.877,8.228,8.685;P<0.01);②57例经前期综合征患者使用舍曲林治疗后HAMA评分较治疗前有显著性下降,治疗8周末与治疗前比较差异具有统计学意义(HAMA 9.6±4.9,减分率69.1±7.5;P<0.01)。治疗2、4、8周末HAMA减分率差异有非常显著意义(P<0.01)。结论舍曲林治疗经前紧张综合症疗效显著。Objective To explore the efficacy of sertraline in the treatment of premenstrual syndrome.Methods Symptom Checklist 90（SCL-90） and the Hamilton Anxiety Scale（HAMA） were used to assess 57 patients with premenstrual tension.Results ①There were sighificant differences in somatization,depression,anricty and other factor for 57 patients with premenstrual syndrone between before and after treatment（t=9.918,9.877,8.228,8.685;P0.01）.②For 57 patients with premenstrual syndrome,HAMA scores were significantly decreased compared with those before treatment,after 8 weeks treatment compared with before treatment differences were statistically significant（HAMA（9.6±4.9）,effective rate of（69.1±7.5）,P0.01）.After treatment for 2,4,8 weekend,there were significant differences in HAMA reduction rate difference（P0.01）.Conclusion Sertraline in the treatment of premenstrual tension syndrome is effective.

关 键 词：经前紧张综合征 舍曲林 症状自评量表 汉密尔顿焦虑量表 

分 类 号：R271.115[医药卫生—中医妇科学]