124株嗜麦芽寡养单胞菌的分布及耐药性  

Drug resistance and distribution of 124 strains of Stenotrophomonas maltophilia

作　　者：魏绪廷[1] 孙启英[1] 刘广丽[1] 

机构地区：[1]泰安市中心医院检验科,山东泰安271000

出　　处：《中华医院感染学杂志》2012年第9期1928-1929,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解医院嗜麦芽寡养单胞菌的耐药性及其分布,为临床治疗及控制医院感染提供依据。方法采用WalkAway 96PLUS自动化微生物鉴定仪进行细菌鉴定及药敏试验,回顾性分析2010年6月-2011年4月临床分离的124株嗜麦芽寡养单胞菌耐药率及分布。结果收集的124株嗜麦芽寡养单胞菌中,对头孢他啶、替卡西林/克拉维酸、磺胺甲噁唑/甲氧苄啶和左氧氟沙星的耐药率分别为46.8%、30.6%、12.1%和9.7%;124株嗜麦芽寡养单胞菌科室分布主要为重症监护病房占70.2%;标本来源主要为痰标本占89.5%。结论嗜麦芽寡养单胞菌是重症监护病房痰液标本中常见的非发酵革兰阴性杆菌,临床上应根据药敏结果合理选用抗菌药物。OBJECTIVE To investigate drug resistance and distribution of Stenotrophomonas maltophilia in hospital,so as to guide the clinical treatment and control nosocomial infections.METHODS Walkaway 96 PLUS automated microbial identification system was used for bacterial identification and susceptibility test.The drug resistance rate and the distribution of 124 strains of S.maltophilia isolated from Jun 2010 to Apr 2011 were retrospectively analyzed.RESULTS The resistance rates of the 124 strains of S.maltophilia to ceftazidime,ticarcillin/clavulanic,sulfamethoxazole / trimethoprim,and levofloxacin were 46.8%,30.6%,12.1%,and 9.7% respectively;totally 124 strains of S.maltophilia were mainly detected from ICU（70.2%）;89.5% of S.maltophilia strains were isolated from sputum.CONCLUSION S.maltophilia is common non-fermenting gram-negative bacilli which can be detected in sputum collected from ICU,antibiotics should be chosen according to drug susceptibility test in the clinical practice.

关 键 词：嗜麦芽寡养单胞菌 抗菌药物 耐药性 

分 类 号：R378[医药卫生—病原生物学]