病毒感染与肥胖  

Viral Infection and Obesity

作　　者：邵惠训[1] 

机构地区：[1]北京实验动物研究中心,北京100012

出　　处：《实验动物科学》2012年第1期48-51,共4页Laboratory Animal Science

摘　　要：肥胖是一种多病原疾病,病毒感染仅仅是引发肥胖的一种因素。已发现9种病毒和生物因子与人类、动物肥胖有关,尚有与肥胖有关的病毒和生物因子有待发现。"感染性肥胖"是一种新的概念,有助于人们将来生产出预防肥胖的疫苗和抗病毒治疗药物。Nine different viruses have been implicated in obesity in animal models,but their role in human obesity has not been established conclusively.Avian adenovirus SMAM-1 is the first virus to be implicated in human obesity.hAd-36 has been found to be more prevalent in obese humans.Chickens inoculated with hAd-37 had much more visceral fat and body fat.Rous-associated virus type 7 induces a syndrome in chickens characterized by stunting and obesity,clearly,not every case of obesity is of infectious origin.However,if a few pathogens can cause obesity,there may be more awaiting discovery.These data give a new perspective to the etiology of obesity and raise the possibility of infection as a contributing factor for obesity in some humans.When such a relationship between pathogens and human obesity is well established,vaccines or antimicrobial agents may be employed to prevent or treat some forms of obesity.

关 键 词：病毒感染 肥胖 感染性肥胖 肥胖基因 瘦素 

分 类 号：S852.65[农业科学—基础兽医学]