针灸对抑郁症患者主观报告结局指标的影响  

Impacts of acupuncture and moxibustion on outcome indeices of depression patients' subjective reports

作　　者：樊凌[1,2] 符文彬[1] 许能贵[3] 刘健华[1] 樊莉[1] 欧爱华 

机构地区：[1]广东省中医院大针灸科,广州510120 [2]广州中医药大学博士后科研流动站 [3]广州中医药大学 [4]广东省中医药科学院

出　　处：《中国针灸》2012年第5期385-389,共5页Chinese Acupuncture & Moxibustion

基　　金：国家自然科学基金项目:81173348;教育部高校博士点专项科研基金联合资助课题项目:20094425110005;广东省自然科学基金项目:07004846;广东省科技厅科技计划项目:2008B030301206

摘　　要：目的:基于患者主观报告结局指标评价临床上针灸治疗抑郁症的疗效。方法:将符合纳入标准的163例抑郁症患者随机分为疏肝调神组、穴位浅刺组和非穴位浅刺组。疏肝调神组取四关穴(合谷、太冲)、百会、印堂进行常规针刺,在四花穴(膈俞、胆俞)艾炷直接灸,最后埋皮内针于心俞、肝俞;穴位浅刺组取穴同疏肝调神组,只是针刺深度较疏肝调神组浅,艾灸时间短于疏肝调神组;非穴位浅刺组取穴为疏肝调神组所取穴位旁开10mm处,操作方法同穴位浅刺组。3组患者每周治疗2次,共治疗12周。观察治疗后及治疗后1个月、3个月症状自评量表(SCL-90)评分,以评价疏肝调神针灸方案对治疗抑郁症的近期效应及中、远期疗效。结果:治疗后各时点,对于躯体化、强迫、抑郁、焦虑、敌对、偏执、精神病性及其他8个维度的评分,疏肝调神组与非穴位浅刺组比较,差异均有统计学意义(均P<0.05);对于抑郁、焦虑、敌对3个维度的评分,疏肝调神组与穴位浅刺组比较,差异均有统计学意义(均P<0.05)。结论:针灸可改善抑郁症患者SCL-90量表评分,运用患者主观报告结局指标可准确地评价临床疗效。Objective To assess the clinical efficacy of acupuncture and moxibustion on depression in view of the outcome indicators of the patient subjective reports.Methods One hundred and sixty-three cases of depression being in compliance with the inclusive standards were randomized into a soothing-liver and regulating-mind group,an acupoint-shallow-puncturing group and a non-acupoint-shallow-puncturing group.In the soothing-liver and re-gulating-mind group,the conventional acupuncture was applied to the four-gate points [Hegu（LI 4） and Taichong（LR 3）],Baihui（GV 20） and Yintang（EX-HN 3）,the direct moxibustion with moxa cone was applied to the four-flower points [Geshu（BL 17）,Danshu（BL 19）].Finally,the intradermal needling was used at Xinshu（BL 15） and Ganshu（BL 18）.In the acupoint-shallow-puncturing group,the acupoints selected were same as those in the soothing-liver and regulating-mind group.But the needle insertion was shallower and the time of moxibustion was shorter.In the non-acupoint-shallow-puncturing group,the spots that were 10 mm lateral to those acupoints in the soothing-liver and regulating-mind group were selected.The operation was same as that in the acupoint-shallow-puncturing group.The treatment was given twice a week in three groups.Totally,12 weeks of treatment were required.The score of symptom checklist 90（SCL-90）,the self-report symptom inventory was observed before treatment,1 month and 3 months after treatment separately so as to assess the corresponding short-term,mid-term and long-term efficacies of the program of acupuncture and moxibustion for soothing the liver and regulating the mind.Results In each time-point after treatment,for the scores of somatization,obsessive-compulsive symptom,interpersonal sensitivity,depression,anxiety,hostility,paranoid ideation,psychoticism and the other 8 dimensionalities,in comparison between the soothing-liver and regulating-mind group and the non-acupoint-shallow-puncturing group,the differences were significant statistical

关 键 词：针灸 抑郁症 患者报告结局 SCL-90量表 临床试验 

分 类 号：R246.6[医药卫生—针灸推拿学]