电针联合托特罗定治疗经尿道前列腺电切术后膀胱过度活动症  

Overactive bladder after transurethral resection of prostate treated with electroacupuncture therapy and Tolterodine

作　　者：申永璋[1] 林霞[2] 林强[3] 

机构地区：[1]日照市人民医院泌尿外科,山东日照276826 [2]日照市人民医院药剂科,山东日照276826 [3]日照市人民医院中医科,山东日照276826

出　　处：《中国针灸》2012年第5期404-408,共5页Chinese Acupuncture & Moxibustion

摘　　要：目的:探讨电针联合托特罗定预防性治疗经尿道前列腺电切术(TURP)后膀胱过度活动症的疗效。方法:将120例行TURP的良性前列腺增生患者随机分为电针组、药物组、针药组及对照组,每组30例。所有患者均在持续硬膜外麻醉下施行TURP术,术后保留尿管5～7天。电针组患者手术当日术前开始针刺,取会阳、次髎、曲骨、会阴,电针治疗30min,每天1次,治疗5～7天。药物组手术当日晨起口服酒石酸托特罗定片2mg,每天2次,治疗5～7天。针药组采用以上电针和药物综合治疗。对照组在术后发生膀胱过度活动时,给予哌替啶50mg肌肉注射,联合山莨菪碱10mg肌肉注射对症治疗。比较各组TURP术后72h内膀胱过度活动的次数和持续时间。结果:电切术后对照组膀胱过度活动次数每日2～4次,每次持续时间5～15min;各治疗组在术后不同时间段膀胱过度活动次数和平均持续时间均少于对照组(P<0.01,P<0.001),电针组与药物组比较差异无统计学意义(均P>0.05);但电切术后24h、24～48h、48～72h针药组膀胱过度活动次数、平均持续时间均明显少于电针组及药物组(P<0.05,P<0.01,P<0.001)。结论:TURP术后早期联合使用电针疗法与口服托特罗定片预防膀胱过度活动症优于单用电针或托特罗定,是解决患者膀胱过度活动安全、有效的方法。Objective To evaluate the therapeutic effect of overactive bladder after transurethral resection of prostate（TURP） preventively treated with electroacupuncture and Tolterodine.Methods One hundred and twenty cases of benign prostate hyperplasia of TURP were randomly divided into an electroacupuncture and medicine group,an electroacupuncture group,a medicine group and a control group,30 cases in each group.All the patients were treated with TURP under the continuous epidural anesthesia,and the catheter was retained for 5-7 days.In electroacupuncture group,before the surgery of the same day,Huiyang（BL 35）,Ciliao（BL 32）,Qugu（CV 2） and Huiyin（CV 1） were acupunctured with electroacupuncture for 30 min,once a day,5-7 days＇ treatment was applied.In medicine group,Tolterodine Tartrate tablet was taken for 2 mg in the morning of surgery day,twice a day and treatment was applied for 5-7 days.In electroacupuncture and medicine group,the comprehensive therapies above in both electroacupuncture group and medicine group were applied.In control group,Pethidine of 50 mg was given by intramuscular injection when bladder was overactive,combined with Anisodamine injection of 10 mg according to the symptoms.The frequency and lasting time of bladder overactivity were compared within 72 hours after TURP in each group.Results After TURP,the frequency of bladder overactivity were 2-4 times a day,and lasted for 5-15 min each time in control group.The frequency and lasting time of bladder overactivity in treatment groups at different time were less than those in control group（P0.01,P0.001）.There was no significant difference in comparison of frequency and lasting time of bladder overactivity between electroacupuncture and medicine group（all P0.05）.The frequency and lasting time of bladder hyperactivity in electroacupuncture and medicine group were less than those in the electroacupuncture group and the medicine group at 24 hours,24-48 hours,48-72 hours after TUPR（P 0.05,P0.01,P 0.001）.Conclusion After TURP

关 键 词：膀胱过度活动症 经尿道前列腺切除术 电针疗法 托特罗定 

分 类 号：R246.2[医药卫生—针灸推拿学]