甲醇钠催化合成2,2,4-三甲基-1,3-戊二醇单异丁酸酯  

SYNTHESIS OF 2,2,4-TRIMETHYL-1,3-PENTANEDIOL MONOISOBUTYRATE CATALYZED BY SODIUM METHOXIDE

作　　者：崇明本 张千 顾海平 何珍娟 陈维斌 王恒秀 

机构地区：[1]宜兴市恒兴精细化工有限公司,江苏宜兴214213

出　　处：《精细石油化工》2012年第2期14-16,共3页Speciality Petrochemicals

摘　　要：研究了合成2,2,4-三甲基-1,3-戊二醇单异丁酸酯的新工艺。以异丁醛为原料,甲醇钠为催化剂,由一段反应工艺实现醇醛缩合、坎尼扎罗两步反应生成目标产物,较好的反应条件为:催化剂用量4g甲醇钠/(200g异丁醛),反应温度60℃,反应时间4h,使得异丁醛的单程转化率达到80%以上,目标产物的选择性达到97%以上。A new technology has been studied to synthesize 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate.Isobutyraldehyde is used as raw material and MeONa as catalyst by one step process,including aldol condensation reaction and Cannizzaro reaction.Under the following optimal conditions： 4 g MeONa as catalyst/（200 g isobutyraldehyde）,60 ℃ reaction temperature and 4 h reaction time,the isobutyraldehyde conversion is above 80% and the target product selectivity is above 97%.

关 键 词：2 2 4-三甲基-1 3-戊二醇单异丁酸酯 异丁醛 甲醇钠 

分 类 号：TQ426.94[化学工程]