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作 者:过建春[1] 李春青[1] 马翔华 荀运浩[1] 石伟珍[1]
机构地区:[1]杭州市第六人民医院中西医结合科,浙江杭州310014 [2]遂昌县中医院,浙江遂昌323300
出 处:《中华中医药学刊》2012年第5期953-955,共3页Chinese Archives of Traditional Chinese Medicine
基 金:国家"十一五"科技重大专项(2008ZX10005-007)
摘 要:目的:探讨慢性乙型重型肝炎患者预后与中医辨证分型的关系。方法:前瞻性调查2009年3月—2010年6月住院的慢性乙型重型肝炎患者97例,对每一例患者进行中医辨证分型并随访24周。结果:气虚瘀黄型、阴虚瘀黄型患者12周病死率明显高于瘀热发黄型(P<0.05),气虚瘀黄型患者12周病死率亦高于湿热发黄型(P=0.020);生存分析显示各组间的累积存活率有显著差异,以气虚、阴虚为主证的患者24周累积存活率明显低于其他证型(P=0.022)。结论慢性乙型重型肝炎的预后与中医辨证分型有着一定的关系。Objective:To explore the relationship between prognosis and TCM syndrome differentiation of severe chronic hepatitis B.Methods:Prospective studies were used to investigate 97 hospitalized cases of severe chronic hepatitis B in our hospital from March 2009 to June 2010.All patients were typed by the symptom differentiation and follow-up visited until death or for at least 24 weeks.Results:The 12-week fatality rates of qi-deficiency related stagnant jaundice and yin-deficiency related stagnant jaundice were much higher than that of heat-stagnant jaundice syndrome(P0.05),The 12-week fatality rate of qi-deficiency related stagnant jaundice was also higher than that of damp-heat jaundice syndrome(P=0.020);there was significant deviation among different groups' cumulative survival rates,the 24-week cumulative survival rates of patients with qi-deficiency or yin-deficiency were obviously lower than other three syndromes(P=0.022).Conclusions:There is some relation between prognosis and TCM syndrome differentiation of severe chronic hepatitis B.
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