吸烟指数与冠状动脉病变程度及预后相关研究  

The Practice investigation of Smoking index and coronary artery disease degree with the discussion of prognosis

作　　者：王光辉[1] 杨军[1] 丁赛良[1] 谭芳[1] 谭小进[1] 吴洁[1] 文格波[2] 

机构地区：[1]南华大学第一附属医院心血管内科,衡阳421001 [2]南华大学

出　　处：《心血管病防治知识（学术版）》2012年第3期4-7,共4页Prevention and Treatment of Cardiovascular Disease

基　　金：湖南省科技厅重点项目资助No.S2009S2032

摘　　要：目的探讨人群吸烟指数与冠状动脉病变程度的相关性及对心血管疾病预后的影响。方法收集和回顾性分析南华大学第一附属医院心导管室(DSA)2010年1月至2011年08月行冠脉造影的1203例可疑冠心病患者,将吸烟指数依据国际通用标准即吸烟支数乘以吸烟年数分为5组;冠状动脉病变程度通过Gensini评分系统定量评定,分为5组。结果随吸烟指数增加冠状动脉病变严重程度及病变范围明显加重,具有显著量效关系,吸烟是冠心病独立危险因素;同时也发现年龄和男性也是冠心病的危险因素。结论吸烟指数与冠状动脉病变程度之间具有明显相关性,严重威胁着人类健康和生命安全,禁烟和控烟刻不容缓。Objective To explore the relationship smoking index and coronary artery disease degree and cardiovascular disease prognosis. Methods Retrospective analysis of collection patients with coronary heart disease （CHD） and it＇ suspected in the Digital Subtraction Angiography （DSA） of the first affiliated hospital of the university of south china in January 2010 to August 2011, 1203 cases of coronary angiography were entered in. according to the international standards of CHD and smoking index Coronary artery pathological damage through the Gensini quantitative evaluation scoring system, divided into 5 groups. Results With smoking index increased coronary artery disease severity and disease extent increase significantly, the relationship has the remarkable concentration-response smoking is independent risk factors of coronary heart disease; It also found that age and men is also the risk factors of coronary heart disease. Conclusion Smoking index and coronary artery pathological changes has a significant relationship between the degree, a serious threat to human health and life safety, quit smoking and tobacco control is urgently needed.

关 键 词：吸烟 冠脉病变程度 危险因素 心血管疾病 控烟 

分 类 号：R541.4[医药卫生—心血管疾病]