生物粘附微球国内外研究进展  

Research Progress in Bioadhesive Microspheres both at Home and Abroad

作　　者：田振坤[1] 高文新[1] 吴伦[1] 冯泽鑫[1] 

机构地区：[1]黑龙江中医药大学药学院,哈尔滨150040

出　　处：《世界科学技术-中医药现代化》2012年第2期1481-1484,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：黑龙江省卫生厅中医药管理局科学技术计划项目(2004G2423-00):新中成药制剂研究;负责人:田振坤

摘　　要：生物粘附微球作为微球给药的一种制剂,具有延长药物的滞留时间、缓释和控释等优势,可以促进药物的吸收,提高药物的生物利用度,从而受到国内外学者的广泛关注。本文主要概述了近年生物粘附微球的常用制备方法和临床应用方面国内外研究进展,并提议建立统一的评价标准。Bioadhesive microspheres are taken as drug delivery microsphere formulations. Bioadhesive microspheres provided extend drug residence time and sustained release, controlled release and other advantages. Bioadhesive mi- crospheres promote drug absorption and improve drug bioavailability. Thus, the bioadhesive mierospheres have caught attention from scholars both at home and abroad. This article mainly summarized advances in bioadhesive microspheres research both at home and abroad in recent years. It included commonly used preparation methods and clinical application of bioadhesive microspheres. This article also gave suggestion on the establishment of unified evaluation standards for bioadhesive microspheres.

关 键 词：微球 生物粘附 研究进展 综述 

分 类 号：R978.61[医药卫生—药品]